Evidence map›Paper›PMID 30970833›Full record

ArticlePolymers2017

Surface Patterning of Gold Nanoparticles on PEG-Based Hydrogels to Control Cell Adhesion.

Fang Ren, Cigdem Yesildag, Zhenfang Zhang, Marga C Lensen

Abstract read
In one paragraph

Article in Polymers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Direct Bottom-UpChemical reviews · 2023
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fang RenNanopatterned Biomaterials, Technische Universität Berlin, Sekr. TC 1, Strasse des 17. Juni 124, Berlin 10623, Germany. renfang_ark@hotmail.com.
Cigdem YesildagNanopatterned Biomaterials, Technische Universität Berlin, Sekr. TC 1, Strasse des 17. Juni 124, Berlin 10623, Germany. cigdem.yesildag@tu-berlin.de.
Zhenfang ZhangNanopatterned Biomaterials, Technische Universität Berlin, Sekr. TC 1, Strasse des 17. Juni 124, Berlin 10623, Germany. Lawrencezzf@hotmail.com.
Marga C LensenNanopatterned Biomaterials, Technische Universität Berlin, Sekr. TC 1, Strasse des 17. Juni 124, Berlin 10623, Germany. Lensen@Chem.TU-Berlin.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on a versatile and easy approach to micro-pattern gold nanoparticles (Au NPs) on 8-arm poly(ethylene glycol)-vinyl sulfone thiol (8PEG-VS-SH) hydrogels, and the application of these patterned Au NPs stripes in controlling cell adhesion. Firstly, the Au NPs were patterned on silicon wafers, and then they were transferred onto reactive, multifunctional 8PEG-VS-SH hydrogels. The patterned, micrometer-sized Au NPs stripes with variable spacings ranging from 20 μm to 50 μm were created by our recently developed micro-contact deprinting method. For this micro-contact deprinting approach, four different PEG-based stamp materials have been tested and it was found that the triblock copolymer PEG-PPG-PEG-(3BC) stamp established the best transfer efficiency and has been used in the ongoing work. After the successful creation of micro-patterns of Au NPs stripes on silicon, the patterns can be transferred conveniently and accurately to 8PEG-VS-SH hydrogel films. Subsequently these Au NPs patterns on 8PEG-VS-SH hydrogels have been investigated in cell culture with murine fibroblasts (L-929). The cells have been observed to adhere to and spread on those nano-patterned micro-lines in a remarkably selective and ordered manner.

Indexed as

cell adhesiongold nanoparticlesmicro-contact deprintingpattern transferpoly(ethylene glycol) hydrogels

Identifiers

PMID30970833
PMCPMC6432185

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.