Evidence map›Paper›PMID 30970805›Full record

ArticlePolymers2017

A Gelated Colloidal Crystal Attached Lens for Noninvasive Continuous Monitoring of Tear Glucose.

Jia-Li Ruan, Cheng Chen, Jian-Hua Shen, Xue-Ling Zhao, Shao-Hong Qian, Zhi-Gang Zhu

Abstract read
In one paragraph

Article in Polymers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  14. Non-gelated polymeric photonic crystal films.Frontiers in chemistry · 2022
    Article
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  18. The Application of Wearable Glucose Sensors in Point-of-Care Testing.Frontiers in bioengineering and biotechnology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jia-Li RuanDepartment of Ophthalmology, EENT Hospital of Fudan University, Shanghai 200031, China. jruan1203@hotmail.com.
Cheng ChenSchool of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China. chencheng@sspu.edu.cn.ORCID 0000-0002-9813-532X
Jian-Hua ShenKey Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China. jianhuashen@ecust.edu.cn.
Xue-Ling ZhaoSchool of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China. xlzhao@sspu.edu.cn.
Shao-Hong QianDepartment of Ophthalmology, EENT Hospital of Fudan University, Shanghai 200031, China. qsh2304@163.com.
Zhi-Gang ZhuSchool of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China. zgzhu@sspu.edu.cn.

Funding

National Natural Science Foundation of China 61471233, 21504051, 21406072Program for Professor of Special Appointment (Eastern Scholar) at SIHLSailing Project and Basic Research Program from Science and Technology Commission of Shanghai Municipality 14YF1410600, 14JC1406402Shuguang an Chenguang project supported by Shanghai Municipal Education Commission 14SG52, 14CG29the international Science and Technology Cooperation Program of China 2015DFA31340the key subject of Shanghai Polytechnic University XXKZD1601
6 · The paper itself

Abstract

Patients of diabetes mellitus urgently need noninvasive and continuous glucose monitoring in daily point-of-care. As the tear glucose concentration has a positive correlation with that in blood, the hydrogel colloidal crystal integrated into contact lens possesses promising potential for noninvasive monitoring of glucose in tears. This paper presents a new glucose-responsive sensor, which consists a crystalline colloidal array (CCA) embedded in hydrogel matrix, attached onto a rigid gas permeable (RGP) contact lens. This novel sensing lens is able to selectively diffract visible light, whose wavelength shifts between 567 and 468 nm according to the alternation of the glucose concentration between 0 and 50 mM and its visible color change between reddish yellow, green, and blue. The detection limit of responsive glucose concentration can be reduced to 0.05 mM. Its combination with a contact lens endows it with excellent biocompatibility and portability, which shows great possibility for it to push the development of glucose-detecting devices into new era.

Indexed as

contact lenscytotoxicitydiffractionhydrogelphotonic crystaltear glucose

Identifiers

PMID30970805
PMCPMC6432312

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.