Evidence map›Paper›PMID 30970594›Full record

ArticleInternational journal of molecular sciences2019

A New Approach for Glyco-Functionalization of Collagen-Based Biomaterials.

Ines Figuereido, Alice Paiotta, Roberta Dal Magro, Francesca Tinelli, Roberta Corti, Francesca Re, Valeria Cassina, Enrico Caneva, Francesco Nicotra, Laura Russo

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ines FiguereidoDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy. ines.figueiredo21@hotmail.com.
Alice PaiottaDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy. alice.paiotta@unimib.it.
Roberta Dal MagroSchool of Medicine and Surgery, University of Milano-Bicocca, 20854 Vedano al Lambro, Italy. roberta.dalmagro@unimib.it.
Francesca TinelliSchool of Medicine and Surgery, University of Milano-Bicocca, 20854 Vedano al Lambro, Italy. francesca.tinelli@unimib.it.
Roberta CortiSchool of Medicine and Surgery, University of Milano-Bicocca, 20854 Vedano al Lambro, Italy. r.corti9@campus.unimib.it.ORCID 0000-0002-4737-7900
Francesca ReSchool of Medicine and Surgery, University of Milano-Bicocca, 20854 Vedano al Lambro, Italy. francesca.re1@unimib.it.ORCID 0000-0003-1374-567X
Valeria CassinaSchool of Medicine and Surgery, University of Milano-Bicocca, 20854 Vedano al Lambro, Italy. valeria.cassina@unimib.it.ORCID 0000-0002-0254-8243
Enrico CanevaUNITECH COSPECT: Comprehensive Substances characterization via advanced sPECTtrometry, 20133 Milan, Italy. enrico.caneva@unimi.it.
Francesco NicotraDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy. francesco.nicotra@unimib.it.
Laura RussoDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy. laura.russo@unimib.it.ORCID 0000-0002-5914-766X

Funding

Horizon 2020 Framework Programme H2020-NMBP-15-2017-760986
6 · The paper itself

Abstract

The cell microenvironment plays a pivotal role in mediating cell adhesion, survival, and proliferation in physiological and pathological states. The relevance of extracellular matrix (ECM) proteins in cell fate control is an important issue to take into consideration for both tissue engineering and cell biology studies. The glycosylation of ECM proteins remains, however, largely unexplored. In order to investigate the physio-pathological effects of differential ECM glycosylation, the design of affordable chemoselective methods for ECM components glycosylation is desirable. We will describe a new chemoselective glycosylation approach exploitable in aqueous media and on non-protected substrates, allowing rapid access to glyco-functionalized biomaterials.

Indexed as

Biocompatible MaterialsCell AdhesionCell Culture TechniquesCell Line, TumorCell ProliferationCell SurvivalCollagenExtracellular Matrix ProteinsGlycosylationHumansBiocompatible MaterialsCollagenExtracellular Matrix Proteinsbiofunctionalizationcell fateECM mimeticsglyco-microenvironmenttissue engineering

Identifiers

PMID30970594
PMCPMC6480084

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.