Evidence map›Paper›PMID 30970554›Full record

ArticlePharmaceutics2019

Age-Related Medicine.

John Wahlich, Mine Orlu, Alpana Mair, Sven Stegemann, Diana van Riet-Nales

Abstract readConference Proceedings
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John WahlichAcademy of Pharmaceutical Sciences, 4 Heydon Road, Great Chishill, Royston, Herts SG8 8SR, UK. John.Wahlich@btinternet.com.ORCID 0000-0002-2590-4634
Mine OrluDepartment of Pharmaceutics, School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK. m.orlu@ucl.ac.uk.
Alpana MairEffective Prescribing and Therapeutics, Health and Social Care Directorate, Scottish Government, Edinburgh EH6 5NL, Scotland, UK. Alpana.Mair@gov.scot.
Sven StegemannInstitute of Process and Particle Engineering, Graz University of Technology, Inffeldgasse 13, 8010 Graz, Austria. sven.stegemann@tugraz.at.
Diana van Riet-NalesMedicines Evaluation Board in the Netherlands, Quality Department, Chemical Pharmaceutical Assessments, P.O. Box 8275, 3503 RG Utrecht, The Netherlands. da.v.riet@cbg-meb.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A meeting organised by the Academy of Pharmaceutical Sciences focussed on the challenges of developing medicines for older adults. International experts discussed the complexity introduced by polypharmacy and multiple morbidities and how the risk⁻benefit ratio of a medicine changes as an individual ages. The way in which regulatory authorities are encouraging the development of age-appropriate medicines was highlighted. Examples were provided of the difficulties faced by the older population with some medicinal products and suggestions given as to how the pharmaceutical scientist can build the requirements of the older population into their development of new medicines, as well as improvements to existing ones.

Indexed as

ageingmultiple morbiditiespharmaceutical sciencespolypharmacyproduct developmentSIMPATHY

Identifiers

PMID30970554
PMCPMC6523864

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.