Evidence map›Paper›PMID 30970178›Full record

ArticleMaternal & child nutrition2019

Folate of pregnant women after a nationwide folic acid supplementation in China.

Xuejuan Zhang, Jufen Liu, Yongsheng Jin, Shuang Yang, Zhijiao Song, Lei Jin, Linlin Wang, Aiguo Ren

Open access · bronzeAbstract read
In one paragraph

Article in Maternal & child nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Periconceptional Supplementation with Folic Acid or Multiple Micronutrients Containing Folic Acid and the Risk for Hypertensive Disorders in Pregnancy.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024
    Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xuejuan ZhangHealth Education Division, Shanxi Children's Hospital/Shanxi Maternal and Child Health Care Hospital, Taiyuan, P. R. China.ORCID 0000-0002-5853-7631
Jufen LiuInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Beijing, China.
Yongsheng JinDepartment of Maternal and Child Health, Health Commission of Shanxi Province, Taiyuan, P. R. China.
Shuang YangDepartment of Child and Adolescences, School of Public Health, Shanxi Medical University, Taiyuan, P. R. China.
Zhijiao SongHealth Education Division, Shanxi Children's Hospital/Shanxi Maternal and Child Health Care Hospital, Taiyuan, P. R. China.
Lei JinInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Beijing, China.
Linlin WangInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Beijing, China.
Aiguo RenInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Beijing, China.
Peking University · CNHealth Commission of Anhui Province · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Folate insufficiency during the periconceptional period increases the risk of neural tube defects (NTDs) in offspring, and folic acid supplementation substantially reduces the risk. Widespread large-scale folic acid supplementation (0.4-mg folic acid tablet) has been adopted as a main strategy to prevent NTDs in China since 2009. We examined folate concentrations in plasma and red blood cells (RBCs) of pregnant women and the factors associated with blood folate concentrations in a population with a high prevalence of NTDs in northern China. A cross-sectional survey was conducted in 2014, and 1,107 pregnant women were recruited from 11 county or city maternal and child health centres across Shanxi province. Microbiological assays were used to determine folate concentrations. Factors associated with blood folate insufficiency were identified. The median (25th and 75th percentiles) folate concentrations were 28.4 (17.6, 45.2) nmol L

Indexed as

Deficiency DiseasesPregnancy ComplicationsAdultChinaCross-Sectional StudiesDietary SupplementsFemaleFolic AcidHealth PromotionHumansPregnancyYoung AdultFolic Acidfolic acid supplementationplasma folatepregnant womenred blood cell folate

Identifiers

PMID30970178
PMCPMC6859985
OpenAlexW2936282709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.