Evidence map›Paper›PMID 30970115›Full record

ArticleJournal of applied oral science : revista FOB2019

Addition of zirconium oxide to Biodentine increases radiopacity and does not alter its physicochemical and biological properties.

Victor Manuel Ochoa-Rodríguez, Mario Tanomaru-Filho, Elisandra Marcia Rodrigues, Juliane Maria Guerreiro-Tanomaru, Rubens Spin-Neto, Gisele Faria

Abstract readEvaluation Study
In one paragraph

Article in Journal of applied oral science : revista FOB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  9. Impact of BiJournal of functional biomaterials · 2019
    Article
  10. The Application ofJournal of functional biomaterials · 2019
    Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Victor Manuel Ochoa-RodríguezUniversidade Estadual Paulista - UNESP, Faculdade de Odontologia de Araraquara, Departamento de Odontologia Restauradora, Araraquara, São Paulo, Brasil.ORCID http://orcid.org/0000-0003-0596-6683
Mario Tanomaru-FilhoUniversidade Estadual Paulista - UNESP, Faculdade de Odontologia de Araraquara, Departamento de Odontologia Restauradora, Araraquara, São Paulo, Brasil.ORCID http://orcid.org/0000-0002-2574-4706
Elisandra Marcia RodriguesUniversidade Estadual Paulista - UNESP, Faculdade de Odontologia de Araraquara, Departamento de Odontologia Restauradora, Araraquara, São Paulo, Brasil.ORCID http://orcid.org/0000-0002-1609-2507
Juliane Maria Guerreiro-TanomaruUniversidade Estadual Paulista - UNESP, Faculdade de Odontologia de Araraquara, Departamento de Odontologia Restauradora, Araraquara, São Paulo, Brasil.ORCID http://orcid.org/0000-0003-0446-2037
Rubens Spin-NetoUniversity of Aarhus, Department of Dentistry, Oral Radiology, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-9562-0610
Gisele FariaUniversidade Estadual Paulista - UNESP, Faculdade de Odontologia de Araraquara, Departamento de Odontologia Restauradora, Araraquara, São Paulo, Brasil.ORCID http://orcid.org/0000-0001-7030-3718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the radiopacity of Biodentine (BD) and BD associated with 15% calcium tungstate (BDCaWO4) or zirconium oxide (BDZrO2), by using conventional and digital radiography systems, and their physicochemical and biological properties. MATERIALS AND

methodsRadiopacity was evaluated by taking radiographs of cement specimens (n=8) using occlusal film, photostimulable phosphor plates or digital sensors. Solubility, setting time, pH, cytocompatibility and osteogenic potential were also evaluated. Data were analyzed using one-way ANOVA and Tukey post-test or two-way ANOVA and Bonferroni post-test (α=0.05).

resultsBD radiopacity was lower than 3 mm Al, while BD ZrO2 and BD CaWO4 radiopacity was higher than 3 mm Al in all radiography systems. The cements showed low solubility, except for BDCaWO4. All cements showed alkaline pH and setting time lower than 34 minutes. MTT and NR assays revealed that cements had greater or similar cytocompatibility in comparison with control. The ALP activity in all groups was similar or greater than the control. All cements induced greater production of mineralized nodules than control.

conclusionsAddition of 15% ZrO2 or CaWO4 was sufficient to increase the radiopacity of BD to values higher than 3 mm Al. BD associated with radiopacifiers showed suitable properties of setting time, pH and solubility, except for BDCaWO4, which showed the highest solubility. All cements had cytocompatibility and potential to induce mineralization in Saos-2 cells. The results showed that adding 15% ZrO2 increases the radiopacity of BD, allowing its radiography detection without altering its physicochemical and biological properties.

Indexed as

Alkaline PhosphataseAnalysis of VarianceAnthraquinonesCalcium CompoundsCell SurvivalHumansHydrogen-Ion ConcentrationMaterials TestingOsteoblastsRadiography, Dental, DigitalReference ValuesReproducibility of ResultsSilicatesSolubilityTime FactorsTungsten CompoundsalizarinAlkaline PhosphataseAnthraquinonesCalcium Compoundscalcium tungstateSilicatestricalcium silicateTungsten CompoundsZirconiumzirconium oxide

Identifiers

PMID30970115
PMCPMC6442842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.