Evidence map›Paper›PMID 30970051›Full record

ArticleMemorias do Instituto Oswaldo Cruz2019

Human sapovirus GI.2 and GI.3 from children with acute gastroenteritis in northern Brazil.

Audrey Cilli, Adriana Luchs, Elcio Leal, Danielle Gill, Flavio Augusto de Pádua Milagres, Shirley Vasconcelos Komninakis, Rafael Brustulin, Maria da Aparecida Rodrigues Teles, Márcia Cristina Alves Brito Sayão Lobato, Rogério Togisaki das Chagas and 6 more

Abstract read
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Audrey CilliInstituto Adolfo Lutz, Centro de Virologia, Núcleo de Doenças Entéricas, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0002-1642-5252
Adriana LuchsInstituto Adolfo Lutz, Centro de Virologia, Núcleo de Doenças Entéricas, São Paulo, SP, Brasil.
Elcio LealUniversidade Federal do Pará, Instituto de Ciências Biológicas, Belém, PA, Brasil.
Danielle GillUniversidade de São Paulo, Instituto de Medicina Tropical, São Paulo, SP, Brasil.
Flavio Augusto de Pádua MilagresUniversidade Federal de Tocantins, Palmas, TO, Brasil.
Shirley Vasconcelos KomninakisFaculdade de Medicina do ABC, Programa de Pós-Graduação em Ciências da Saúde, Santo André, SP, Brasil.
Rafael BrustulinUniversidade Federal de Tocantins, Palmas, TO, Brasil.
Maria da Aparecida Rodrigues TelesLaboratório Central de Saúde Pública do Tocantins, Palmas, TO, Brasil.
Márcia Cristina Alves Brito Sayão LobatoLaboratório Central de Saúde Pública do Tocantins, Palmas, TO, Brasil.
Rogério Togisaki das ChagasLaboratório Central de Saúde Pública do Tocantins, Palmas, TO, Brasil.
Maria de Fátima Neves Dos Santos AbrãoLaboratório Central de Saúde Pública do Tocantins, Palmas, TO, Brasil.
Cassia Vitória de Deus Alves SoaresLaboratório Central de Saúde Pública do Tocantins, Palmas, TO, Brasil.
Xutao DengBlood Systems Research Institute, San Francisco, CA, USA.
Eric DelwartBlood Systems Research Institute, San Francisco, CA, USA.
Ester Cerdeira SabinoUniversidade de São Paulo, Instituto de Medicina Tropical, São Paulo, SP, Brasil.
Antonio Charlys da CostaUniversidade de São Paulo, Instituto de Medicina Tropical, São Paulo, SP, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human sapoviruses (HSaV) are considered important causative agents of acute gastroenteritis in humans worldwide. However, knowledge of the genetic characteristics of the whole genome of HSaV in Brazil is limited. Here we report the complete genome sequences of six HSaVs GI.2 and two GI.3 strains obtained from children with acute gastroenteritis in the Northern region of Brazil. Next generation sequencing was used to obtain the full genome and molecular characterization of the genome was performed. Phylogenetic analysis of the genome was also performed. Only one complete HSaV GI.2 genome characterization in the country precedes that of the present study. This is the first complete genome sequence of genotype GI.3 in Brazil. The data obtained in this investigation can contribute to the augmentation of the database on the molecular diversity of HSaVs strains circulating in Brazil, and to the improvement of current typing protocols.

Indexed as

Acute DiseaseBrazilCaliciviridae InfectionsChildGastroenteritisGenotypeHigh-Throughput Nucleotide SequencingHumansPhylogenySapovirusSequence Analysis, DNA

Identifiers

PMID30970051
PMCPMC6452520

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.