Evidence map›Paper›PMID 30969390›Full record

ArticleCytotechnology2019

Apoptosis-inducing activities of Halopteris scoparia L. Sauvageau (Brown algae) on cancer cells and its biosafety and antioxidant properties.

Adem Güner, Ayşe Nalbantsoy, Atakan Sukatar, Nefise Ülkü Karabay Yavaşoğlu

Open access · bronzeAbstract read
In one paragraph

Article in Cytotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 36 citations in OpenAlex.

  1. CombinedArhiv za higijenu rada i toksikologiju · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Adem GünerFaculty of Science and Art, Department of Biology, Giresun University, Güre, Giresun, 28200, Turkey. ademeguner@gmail.com.
Ayşe NalbantsoyFaculty of Engineering, Department of Bioengineering, Ege University, Bornova, Izmir, 35100, Turkey.
Atakan SukatarFaculty of Science, Department of Biology, Ege University, Bornova, Izmir, 35100, Turkey.
Nefise Ülkü Karabay YavaşoğluFaculty of Science, Department of Biology, Ege University, Bornova, Izmir, 35100, Turkey.
Ege University · TRGiresun University · TR

Funding

Ege University BAP project 2013/ FEN/ 015TÜBİTAK 2211 Scholarship
6 · The paper itself

Abstract

The aim of this study was to reveal the biological activities and in vivo toxicity profiles of n-hexane, chloroform and methanol extracts of brown algae Halopteris scoparia L. Sauvageau. In this study, extracts were tested for their phytochemical contents and antioxidant activities. The cytotoxic activities of the extracts against cervical adenocarcinoma (HeLa), colon colorectal adenocarcinoma (CaCo-2) and breast adenocarcinoma (MCF7) cells were assessed by MTT assay and total RNAs derived from cell lines to analyze gene expression were analyzed by Real Time Ready Human Apoptosis Panel 96. Also, in vivo toxicity and irritation effects of extracts were evaluated by LD

Indexed as

AnticancerAntioxidantApoptosisBrown algaeHalopteris scopariaHET-CAM assay

Identifiers

PMID30969390
PMCPMC6546795
OpenAlexW2940032148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.