Evidence map›Paper›PMID 30969363›Full record

ArticlePediatric nephrology (Berlin, Germany)2019

Risk factors for early onset peritonitis: the SCOPE collaborative.

Mahima Keswani, Allison C Redpath Mahon, Troy Richardson, Jonathan Rodean, Olivera Couloures, Abigail Martin, Richard T Blaszak, Bradley A Warady, Alicia Neu, SCOPE Investigators

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Dynamic changes in serum albumin and ferritin indicate higher risk of early-onset peritonitis in peritoneal dialysis patients.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2026
    Article
  3. Article
  4. Article
  5. Care of the pediatric patient on chronic peritoneal dialysis.Pediatric nephrology (Berlin, Germany) · 2022
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Mahima KeswaniAnn and Robert H. Lurie Children's Hospital of Chicago, 225 East Chicago Avenue, Chicago, IL, 60611, USA. mkeswani@luriechildrens.org.ORCID 0000-0002-2717-1788
Allison C Redpath MahonAmerican Family Children's Hospital, Madison, WI, USA.
Troy RichardsonChildren's Hospital Association, Lenexa, KS, USA.
Jonathan RodeanChildren's Hospital Association, Lenexa, KS, USA.
Olivera CoulouresYale New Haven Children's Hospital, New Haven, CT, USA.
Abigail MartinNemours A.I. duPont Hospital for Children, Wilmington, DE, USA.
Richard T BlaszakArkansas Children's Hospital, Little Rock, AR, USA.
Bradley A WaradyChildren's Mercy Kansas City, Kansas City, MO, USA.
Alicia NeuJohn's Hopkins Children's Center, Baltimore, MD, USA.
SCOPE Investigators
Arkansas Children's Hospital · USYale New Haven Hospital · USChildren's Hospital Association · USChildren's Mercy Hospital · USJohns Hopkins University · USLurie Children's Hospital · USLurie Children's Hospital · USUniversity of Wisconsin American Family Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeritoneal dialysis (PD) is the preferred chronic dialysis modality amongst pediatric patients. Peritonitis is a devastating complication of PD. Adult data demonstrates early onset peritonitis (EP) is associated with higher rates of subsequent peritonitis and technique failure. Limited data exists regarding EP in the pediatric population, here defined as peritonitis occurring within 60 days of catheter insertion.

methodsPD catheter insertion practices and EP episodes were examined from the Standardizing Care to Improve Outcomes in Pediatric End Stage Renal Disease (SCOPE) collaborative database.

resultsThere were 98 episodes of EP amongst 1106 PD catheters inserted. Multivariable analysis demonstrated a significant association between early use of the PD catheter and EP (P = 0.001). Age less than 1 year at the time of catheter insertion (P < 0.001), first catheter placed (P < 0.001) for the patient, use of a plastic adapter (P = 0.003), placement of sutures at the exit site (ES) (P = 0.032), and dressing change prior to 7 days post-operatively (P < 0.001) were all significantly associated with early PD catheter use. Concurrent placement of a hemodialysis catheter was associated with a decreased risk for early PD catheter use (P = 0.010).

conclusionsIn this large cohort of pediatric PD recipients, 8.4% of PD catheters were associated with the development of EP. The finding of an association between early use of the PD catheter and EP represents a potentially modifiable risk factor to reduce infection rates within this patient population.

Indexed as

Age FactorsCatheter-Related InfectionsCatheters, IndwellingFemaleHumansInfantKidney Failure, ChronicMalePeritoneal DialysisPeritonitisProspective StudiesRisk AssessmentRisk FactorsTime FactorsDialysisEarly onset peritonitisPediatricPeritoneal

Identifiers

PMID30969363
OpenAlexW2937898679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.