ArticleJAMA psychiatry2019
Toward High Reproducibility and Accountable Heterogeneity in Schizophrenia Research.
Abstract readEditorialComment
In one paragraph
Article in JAMA psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Ancestral, Pregnancy, and Negative Early-Life Risks Shape Children's Brain (Dis)similarity to Schizophrenia.Biological psychiatry · 2023Pooled it
- Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11.2 deletion syndrome: A review of ENIGMA findings.Psychiatry and clinical neurosciences · 2022Pooled it
- Separating Clinical and Subclinical Depression by Big Data Informed Structural Vulnerability Index and Its impact on Cognition: ENIGMA Dot Product.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2022Pooled it
- ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries.Translational psychiatry · 2020Pooled it
- Genetic Variants from Large Cohorts and Familial Studies Implicate Common Mechanisms in Schizophrenia.Biology · 2026Review
- Peripheral Microvascular and Cerebral White Matter Dysfunction in Schizophrenia: Implications of a Body-Brain Endothelial Pathophysiology.Schizophrenia bulletin · 2025Article
- Neuroanatomical Correlates of Negative Symptoms in Schizophrenia.bioRxiv : the preprint server for biology · 2025Article
- Microdosing Psychedelics to Restore Synaptic Density in Schizophrenia.International journal of molecular sciences · 2025Review
- Unveiling Promising Neuroimaging Biomarkers for Schizophrenia Through Clinical and Genetic Perspectives.Neuroscience bulletin · 2024Review
- Regional Vulnerability Indices in Youth With Persistent and Distressing Psychoticlike Experiences.JAMA network open · 2023Article
- The future of diagnosis in clinical neurosciences: Comparing multiple sclerosis and schizophrenia.European psychiatry : the journal of the Association of European Psychiatrists · 2023Review
- Brain deficit patterns of metabolic illnesses overlap with those for major depressive disorder: A new metric of brain metabolic disease.Human brain mapping · 2023Article
- Single-nucleus RNA sequencing of midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypes.Molecular psychiatry · 2022Article
- Brain-wide versus genome-wide vulnerability biomarkers for severe mental illnesses.Human brain mapping · 2022Article
- Derivation and utility of schizophrenia polygenic risk associated multimodal MRI frontotemporal network.Nature communications · 2022Article
- Translating ENIGMA schizophrenia findings using the regional vulnerability index: Association with cognition, symptoms, and disease trajectory.Human brain mapping · 2022Article
- ENIGMA-DTI: Translating reproducible white matter deficits into personalized vulnerability metrics in cross-diagnostic psychiatric research.Human brain mapping · 2022Article
- Clinical and cortical similarities identified between bipolar disorder I and schizophrenia: A multivariate approach.Frontiers in human neuroscience · 2022Article
Corrections and comments
- Comment on
Authors and funding
3 authors.
Peter KochunovMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore.
Paul M ThompsonImaging Genetics Center, Mark & Mary Stevens Institute for Neuroimaging and Informatics, University of Southern California Keck School of Medicine, Los Angeles.
L Elliot HongMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore.
Funding
The Effects of Kynurenine Aminotransferase Inhibition in People with SchizophreniaP50MH103222 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI SCHWARCZ, ROBERT · 2014 to 2023
$25.2MSOLAR-Eclipse Computational Tools for Imaging GeneticsR01EB015611 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOCHUNOV, PETER V. · 2012 to 2024
$5.0MAmish Connectome Project on Mental IllnessU01MH108148 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT, KOCHUNOV, PETER V. · 2015 to 2018
$4.3MTowards Multisystem-Brain Successful Aging in Schizophrenia SpectrumR01MH116948 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HONG, L ELLIOT ELLIOT · 2018 to 2022
$3.7MThe Role of Stress-Immune-Connectome Disruption in Mechanisms of Chinese Early Schizophrenia SpectrumR01MH112180 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT · 2017 to 2021
$1.0MHybrid GPU/CPU Computing Resource to Support Connectomic and GenomicsS10OD023696 · OD · UNIVERSITY OF MARYLAND BALTIMORE · PI KOCHUNOV, PETER V. · 2018 to 2018
$593kNIBIB NIH HHS R01 EB015611NIH HHS S10 OD023696NIMH NIH HHS P50 MH103222NIMH NIH HHS R01 MH112180NIMH NIH HHS R01 MH116948NIMH NIH HHS U01 MH108148
Abstract
PubMed holds no abstract for this paper.
Indexed as
SchizophreniaBrainHumansMultifactorial InheritanceReproducibility of ResultsSchizophrenic Psychology
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.