Evidence map›Paper›PMID 30969170›Full record

ArticleeLife2019

Byungchul Kim, Yen-Chih Wang, Charles W Hespen, Juliel Espinosa, Jeanne Salje, Kavita J Rangan, Deena A Oren, Jin Young Kang, Virginia A Pedicord, Howard C Hang

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it, 133 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Frontiers in microbiology · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Journal of bacteriology · 2025
    Article
  16. Effects ofVeterinary sciences · 2025
    Article
  17. Review
  18. Article
  19. Review
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Byungchul KimLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, United States.ORCID 0000-0002-0207-7357
Yen-Chih WangLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, United States.
Charles W HespenLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, United States.ORCID 0000-0001-5466-0280
Juliel EspinosaLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, United States.ORCID 0000-0003-2104-5331
Jeanne SaljeCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Kavita J RanganLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, United States.
Deena A OrenStructural Biology Resource Center, The Rockefeller University, New York, United States.
Jin Young KangLaboratory of Molecular Biophysics, The Rockefeller University, New York, United States.
Virginia A PedicordLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, United States.
Howard C HangLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, United States.ORCID 0000-0003-4053-5547
Rockefeller University · USUniversity of Cambridge · GBUniversity of Oxford · GB

Funding

Immunity and Infectious DiseaseT32AI070084 · NIAID · ROCKEFELLER UNIVERSITY · PI Michel C Nussenzweig · 2008 to 2026
$3.3M
Elucidation of Commensal Bacteria Mechanisms Required for Host ProtectionR01GM103593 · NIGMS · ROCKEFELLER UNIVERSITY · PI HANG, HOWARD C · 2013 to 2020
$2.8M
Acquisition of a DeltaVision OMX SR 3D SIM system for super-resolution imagingS10RR031855 · NCRR · ROCKEFELLER UNIVERSITY · PI NORTH, ALISON JANE · 2011 to 2011
$600k
Distal gut microbiome targets of host anti-proteolytic proteins during colitisR21AI156674 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI HANG, HOWARD C · 2021 to 2022
$488k
Mechanistic analysis and engineering probiotic bacteria with SagAF32AT010087 · NCCIH · ROCKEFELLER UNIVERSITY · PI HESPEN, CHARLES W · 2019 to 2021
$200k
Crystallization Robot for the Structural Biology Resource Center at RockefellerS10RR027037 · NCRR · ROCKEFELLER UNIVERSITY · PI OREN, DEENA ABELLS · 2010 to 2010
$147k
Cancer Research Institute Postdoctoral fellowshipNCCIH NIH HHS F32 AT010087NCCIH NIH HHS F32AT010087NCRR NIH HHS S10 RR027037NCRR NIH HHS S10 RR031855NIAID NIH HHS R21 AI156674NIAID NIH HHS T32 AI070084NIGMS NIH HHS R01 GM103593NIGMS NIH HHS R01GM103593
6 · The paper itself

Abstract

We discovered that

Indexed as

Antigens, BacterialCrystallography, X-RayEnterococcus faeciumHEK293 CellsHumansN-Acetylmuramoyl-L-alanine AmidaseNod2 Signaling Adaptor ProteinPeptidoglycanProtein ConformationAntigens, BacterialN-Acetylmuramoyl-L-alanine AmidaseNOD2 protein, humanNod2 Signaling Adaptor ProteinPeptidoglycanbiochemistrychemical biologycommensal bacteriaEnterococcusintestinal barriermicrobiotaNOD2peptidoglycan

Identifiers

PMID30969170
PMCPMC6483599
OpenAlexW2937340088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.