Evidence map›Paper›PMID 30969149›Full record

ArticleJournal of aerosol medicine and pulmonary drug delivery2019

Multiprobe Nuclear Imaging of the Cystic Fibrosis Lung as a Biomarker of Therapeutic Effect.

Timothy E Corcoran, Alex S Huber, Michael M Myerburg, Daniel J Weiner, Landon W Locke, Ryan T Lacy, Lawrence Weber, Michael R Czachowski, Darragh J Johnston, Ashok Muthukrishnan and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of aerosol medicine and pulmonary drug delivery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Mucus, mucins, and cystic fibrosis.Pediatric pulmonology · 2019
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Timothy E Corcoran1Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Alex S Huber2Department of Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania.
Michael M Myerburg1Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Daniel J Weiner4Pulmonary Medicine, Allergy, and Immunology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Landon W Locke5Department of Microbial Infection and Immunity, Ohio State University, Columbus, Ohio.
Ryan T Lacy3Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania.
Lawrence Weber6Nuclear Medicine Department, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Michael R Czachowski6Nuclear Medicine Department, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Darragh J Johnston2Department of Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania.
Ashok Muthukrishnan7Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Alison T Lennox1Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Joseph M Pilewski1Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
University of Pittsburgh · USThe Ohio State University · US

Funding

Translational StudiesP30DK072506 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALCORN, JOHN F · 2005 to 2017
$12.5M
Imaging Airway Liquid Absorption in Cystic FibrosisR01HL108929 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CORCORAN, TIMOTHY E · 2011 to 2015
$1.9M
Building Multilevel Models of Therapeutic Response in the LungsU01HL131046 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CORCORAN, TIMOTHY E, PARKER, ROBERT S. · 2016 to 2019
$1.7M
NHLBI NIH HHS R01 HL108929NIDDK NIH HHS P30 DK072506
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mucociliary ClearanceAdministration, InhalationAdolescentAdultBiomarkersCase-Control StudiesChildCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorFemaleHumansLungMaleMannitolProspective StudiesPseudomonas InfectionsBiomarkersCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorMannitolSaline Solution, Hypertonicairway surface liquidCFTRDTPAmucociliary clearance

Identifiers

PMID30969149
PMCPMC6685188
OpenAlexW2938422313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.