ArticleJournal of magnetic resonance imaging : JMRI2019
3D quantitative synthetic MRI-derived cortical thickness and subcortical brain volumes: Scan-rescan repeatability and comparison with conventional T
Article in Journal of magnetic resonance imaging : JMRI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- A DERIVED RELAXATION CONTRAST FROM SYNTHETIC MRI FOR DETECTING NETWORK MICROSTRUCTURAL VULNERABILITY.bioRxiv : the preprint server for biology · 2026Article
- Clinical Image Quality and Reader Variability in 3D Synthetic Brain MRI Compared with Conventional MRI.Tomography (Ann Arbor, Mich.) · 2026Article
- Assessment of magnetic resonance image compilation (MAGiC) abilities of therapeutic selection and prediction on recurrence risk factors and short-term treatment efficacy in cervical cancer.La Radiologia medica · 2025Article
- Longitudinal investigation of neurobiological changes across pregnancy.Communications biology · 2025Article
- Zero-DeepSub: Zero-shot deep subspace reconstruction for rapid multiparametric quantitative MRI using 3D-QALAS.Magnetic resonance in medicine · 2024Article
- Time-efficient, high-resolution 3T whole-brain relaxometry using 3D-QALAS with wave-CAIPI readouts.Magnetic resonance in medicine · 2024Article
- Reproducibility of quantitative ADC, T1, and T2 measurement on the cerebral cortex: Utility of whole brain echo-planar DWI with compressed SENSE (EPICS-DWI): A pilot study.European journal of radiology open · 2023Article
- SSL-QALAS: Self-Supervised Learning for rapid multiparameter estimation in quantitative MRI using 3D-QALAS.Magnetic resonance in medicine · 2023Article
- Brain Parcellation Repeatability and Reproducibility Using Conventional and Quantitative 3D MR Imaging.AJNR. American journal of neuroradiology · 2023Article
- Pediatric magnetic resonance imaging: faster is better.Pediatric radiology · 2023Review
- Validation of cross-sectional and longitudinal ComBat harmonization methods for magnetic resonance imaging data on a travelling subject cohort.Neuroimage. Reports · 2022Article
- Synthetic MRI in children with tuberous sclerosis complex.Insights into imaging · 2022Article
- Advantages of Using Both Voxel- and Surface-based Morphometry in Cortical Morphology Analysis: A Review of Various Applications.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022Review
- Relaxation time of brain tissue in the elderly assessed by synthetic MRI.Brain and behavior · 2022Article
- Silent zero TE MR neuroimaging: Current state-of-the-art and future directions.Progress in nuclear magnetic resonance spectroscopy · 2021Review
- 3D Quantitative Synthetic MRI in the Evaluation of Multiple Sclerosis Lesions.AJNR. American journal of neuroradiology · 2021Article
- Repeatability and reproducibility of human brain morphometry using three-dimensional magnetic resonance fingerprinting.Human brain mapping · 2021Article
- Brain Volumetric Measurements in Children With Attention Deficit Hyperactivity Disorder: A Comparative Study Between Synthetic and Conventional Magnetic Resonance Imaging.Frontiers in neuroscience · 2021Article
- Brain-printing biometrics underlying mechanism as an early diagnostic technique for Alzheimer's disease neurodegenerative type.Current research in physiology · 2021Review
- Variability and Standardization of Quantitative Imaging: Monoparametric to Multiparametric Quantification, Radiomics, and Artificial Intelligence.Investigative radiology · 2020Review
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Authors and funding
16 authors.
Funding
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Abstract
backgroundPrevious quantitative synthetic MRI of the brain has been solely performed in 2D. PURPOSE: To evaluate the feasibility of the recently developed sequence 3D-QALAS for brain cortical thickness and volumetric analysis. STUDY TYPE: Reproducibility/repeatability study. SUBJECTS: Twenty-one healthy volunteers (35.6 ± 13.8 years). FIELD STRENGTH/SEQUENCE: 3D T ASSESSMENT: FreeSurfer and FIRST were used to measure cortical thickness and volume of subcortical structures, respectively. Agreement with FSPGR and scan-rescan repeatability were evaluated for 3D-QALAS. STATISTICAL TESTS: Percent relative difference and intraclass correlation coefficient (ICC) were used to assess reproducibility and scan-rescan repeatability of the 3D-QALAS sequence-derived measurements.
resultsPercent relative difference compared with FSPGR in cortical thickness of the whole cortex was 3.1%, and 89% of the regional areas showed less than 10% relative difference in cortical thickness. The mean ICC across all regions was 0.65, and 74% of the structures showed substantial to almost perfect agreement. For volumes of subcortical structures, the median percent relative differences were lower than 10% across all subcortical structures, except for the accumbens area, and all structures showed ICCs of substantial to almost perfect agreement. For the scan-rescan test, percent relative difference in cortical thickness of the whole cortex was 2.3%, and 97% of the regional areas showed less than 10% relative difference in cortical thickness. The mean ICC across all regions was 0.73, and 80% showed substantial to almost perfect agreement. For volumes of subcortical structures, relative differences were less than 10% across all subcortical structures except for the accumbens area, and all structures showed ICCs of substantial to almost perfect agreement. DATA
conclusion3D-QALAS could be reliably used for measuring cortical thickness and subcortical volumes in most brain regions. LEVEL OF EVIDENCE: 3 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2019;50:1834-1842.
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