Evidence map›Paper›PMID 30968822›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2019

Outbreak of hepatitis A virus infection in Taiwan, June 2015 to September 2017.

Wan-Chin Chen, Po-Hsun Chiang, Yu-Hsin Liao, Lin-Ching Huang, Ying-Jung Hsieh, Chu-Ming Chiu, Yi-Chun Lo, Chin-Hui Yang, Jyh-Yuan Yang

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  9. Article
  10. Review
  11. Lessons from intensified surveillance of viral hepatitis A, Israel, 2017 and 2018.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2021
    Article
  12. Co-Occurrence of Hepatitis A Infection and Chronic Liver Disease.International journal of molecular sciences · 2020
    Review
  13. Hepatitis A outbreak among men who have sex with men, Shinjuku, Japan, 2018.Western Pacific surveillance and response journal : WPSAR
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wan-Chin ChenOffice of Preventive Medicine, Centers for Disease Control, Ministry of Health and Welfare, Taipei City, Taiwan.
Po-Hsun ChiangPoloWang Bio. Inc, New Taipei City, Taiwan.
Yu-Hsin LiaoCenter for Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei City, Taiwan.
Lin-Ching HuangOffice of Preventive Medicine, Centers for Disease Control, Ministry of Health and Welfare, Taipei City, Taiwan.
Ying-Jung HsiehDivision of Acute Infectious Diseases, Centers for Disease Control, Ministry of Health and Welfare, Taipei City, Taiwan.
Chu-Ming ChiuDivision of Acute Infectious Diseases, Centers for Disease Control, Ministry of Health and Welfare, Taipei City, Taiwan.
Yi-Chun LoOffice of Deputy Director-General, Centers for Disease Control, Ministry of Health and Welfare, Taipei City, Taiwan.
Chin-Hui YangDivision of Acute Infectious Diseases, Centers for Disease Control, Ministry of Health and Welfare, Taipei City, Taiwan.
Jyh-Yuan YangCenter for Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei City, Taiwan.
Ministry of Health and Welfare · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Taiwan Centers for Disease Control (CDC) were notified of increasing acute hepatitis A (AHA) in June 2015. Serum and/or stool from AHA patients and sewage samples were tested for hepatitis A virus (HAV). We defined outbreak cases as AHA patients with illness onset after June 2015 and with an HAV sequence less than 0.5% different from that of the TA-15 outbreak strain. We analysed characteristics and food exposures between outbreak and non-outbreak cases between January 2014 (start of enhanced surveillance) and February 2016. From June 2015 to September 2017, there were 1,563 AHA patients with a median age of 31 years (interquartile range (IQR): 26-38); the male-to-female ratio was 8.8 and 585 (37%) had human immunodeficiency virus (HIV) infection. TA-15 was detected in 82% (852/1,033) of AHA patients, and 14% (74/540) of sewage samples tested since July 2015. Infection with the TA-15 strain was associated with having HIV, sexually transmitted infections (STI), recent oral-anal sex and men who have sex with men (MSM). The Taiwan CDC implemented an HAV vaccine campaign starting from October 2016 where 62% (15,487/24,879) of people at risk were vaccinated against HAV. We recommend HAV vaccination for at-risk populations and continuous surveillance to monitor control measures.

Indexed as

Disease OutbreaksAdultAge DistributionComorbidityDisease NotificationFemaleHepatitis AHepatitis A virusHIV InfectionsHomosexuality, MaleHumansMaleMolecular Sequence DataPhylogenyRisk FactorsRNA, ViralRNA, Viralhepatitis aHIVhuman immunodeficiency virusoutbreakssexually transmitted infections

Identifiers

PMID30968822
PMCPMC6462791
OpenAlexW2930327448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.