Evidence map›Paper›PMID 30968800›Full record

ArticleDevelopment and psychopathology2019

Inhibitory control and emotion dysregulation: A framework for research on anxiety.

Elise M Cardinale, Anni R Subar, Melissa A Brotman, Ellen Leibenluft, Katharina Kircanski, Daniel S Pine

Abstract read
In one paragraph

Article in Development and psychopathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Cognitive Functioning in Youth with Anxiety Disorders: A Systematic Review.Clinical child and family psychology review · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elise M CardinaleEmotion and Development Branch,National Institute of Mental Health,Bethesda, MD,USA.
Anni R SubarEmotion and Development Branch,National Institute of Mental Health,Bethesda, MD,USA.
Melissa A BrotmanEmotion and Development Branch,National Institute of Mental Health,Bethesda, MD,USA.
Ellen LeibenluftEmotion and Development Branch,National Institute of Mental Health,Bethesda, MD,USA.
Katharina KircanskiEmotion and Development Branch,National Institute of Mental Health,Bethesda, MD,USA.
Daniel S PineEmotion and Development Branch,National Institute of Mental Health,Bethesda, MD,USA.

Funding

fMRI Studies Of Pediatric Mood And Anxiety DisordersZIAMH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$41.5M
Unit on Neuroscience and Novel TherapeuticsZIAMH002969 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BROTMAN, MELISSA · 2019 to 2025
$13.8M
Intramural NIH HHS Z99 MH999999Intramural NIH HHS ZIA MH002781NIMH NIH HHS ZIA MH002781
6 · The paper itself

Abstract

While emotional dysregulation is a broad construct, the current paper adopts a narrow approach to facilitate translational neuroscience research on pediatric anxiety. The paper first presents data on an adapted version of the antisaccade task and then integrates these data into a research framework. Data on an adapted version of the antisaccade task were collected in 57 youth, including 35 seeking treatment for an anxiety disorder. Associations were examined between performance on the antisaccade task and (a) age, (b) performance on other cognitive-control tasks (i.e., the stop-signal delay and flanker tasks), and (c) level of anxiety symptoms. Better performance on the antisaccade task occurred in older relative to younger subjects and correlated with better performance on the flanker task. Across the 57 youth, higher levels of anxiety correlated with shorter latency for correct antisaccades. These data can be placed within a three-step framework for translational neuroscience research. In the first step, a narrow index of emotion dysregulation is targeted. In the second step, this narrow index is linked to other correlated indicators of the same underlying narrow latent construct. In the third and final step, associations are examined with clinical outcomes and response to treatment.

Indexed as

Inhibition, PsychologicalAdolescentAnxietyAnxiety DisordersChildEmotionsExecutive FunctionFemaleHumansMaleReaction TimeSaccadesantisaccade taskanxiety eye movementsinhibitory controllatency

Identifiers

PMID30968800
PMCPMC7439288

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.