Evidence map›Paper›PMID 30968321›Full record

ArticleJournal of behavioral medicine2019

Cardiovascular disease risk factors are elevated among a cohort of young sexual and gender minorities in Chicago.

Ethan Morgan, Richard D'Aquila, Mercedes R Carnethon, Brian Mustanski

Open access · greenAbstract read
In one paragraph

Article in Journal of behavioral medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ethan MorganInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, 625 N Michigan Ave, Suite 14-061, Chicago, IL, 60611, USA.ORCID http://orcid.org/0000-0001-7189-680X
Richard D'AquilaDepartment of Medicine, Division of Infectious Diseases and HIV Translational Research Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Mercedes R CarnethonDepartment of Preventative Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Brian MustanskiInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, 625 N Michigan Ave, Suite 14-061, Chicago, IL, 60611, USA. brian@northwestern.edu.
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Virology and Immunology Technology CoreP30AI117943 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Kathryn Rose Macapagal · 2015 to 2026
$38.4M
The RADAR cohort study of multilevel Influences on HIV and substance useU01DA036939 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Brian Mustanski, Michael E Newcomb · 2014 to 2026
$29.5M
Substance Use, Stress, and HIV Influences on Systemic Inflammation Among Young Men Who Have Sex With MenF32DA046313 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MORGAN, ETHAN · 2018 to 2019
$119k
NCATS NIH HHS UL1 TR001422NIAID NIH HHS P30 AI117943NIDA NIH HHS F32 DA046313NIDA NIH HHS F32DA046313NIDA NIH HHS U01 DA036939NIDA NIH HHS U01DA036939
6 · The paper itself

Abstract

To date, little research has examined cardiovascular (CVD) risk among young sexual and gender minorities, a population which behavioral research has suggested may be at unique risk of poor CVD outcomes. We assessed behavioral risk factors and biomarkers of CVD risk among young sexual and gender minorities (YSGM) aged 16-29 in Chicago who are participants in the RADAR cohort (analytic N = 936). Multiplex cytokine and inflammatory biomarker assays were run on plasma from all HIV+ participants and demographically-matched HIV- participants (n = 237). Geographic data were used to assess mean C-reactive protein (CRP) level per community area of residence in Chicago. YSGM in this cohort exhibited lower rates of obesity (19.2% in RADAR vs. 35.7% in earlier studies of heterosexual youth) and comparable rates of past 30-day tobacco use (37.9 vs. 38.1%). Conversely, higher rates were observed among several other risk factors including C-reactive protein (mean = 6.9 mg/L vs. 2.1 mg/L), marijuana use (72.5 vs. 45.3%), perceived stress (mean = 15.5 vs. 14.2), and HIV (20.0 vs. < 1% nationally). Finally, we observed geographic heterogeneity in mean CRP values by community area across the Chicago region with the highest and lowest values both found in neighborhoods on the North side of the city. In sum, these analyses demonstrate that YSGM may be at increased risk of CVD beginning from an early age. Future research should assess whether sexual minority-related stressors increase long-term CVD risk and should also longitudinally study the role of multiple risk factors on CVD morbidity and mortality among YSGM.

Indexed as

Sexual and Gender MinoritiesAdolescentAdultBiomarkersCardiovascular DiseasesChicagoCohort StudiesC-Reactive ProteinFemaleHumansMaleMarijuana SmokingObesityRisk FactorsYoung AdultBiomarkersC-Reactive ProteinCardiovascular diseaseHIVInflammationMSM

Identifiers

PMID30968321
PMCPMC6785361
OpenAlexW2940410560

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.