Evidence map›Paper›PMID 30967972›Full record

ArticleEuropean journal of microbiology & immunology2019

Multidrug-Resistant Tuberculosis in Burkina Faso from 2006 to 2017: Results of National Surveys.

Souba Diandé, Gisèle Badoum, Adjima Combary, Issaka Zombra, Tandaogo Saouadogo, Léon T Sawadogo, Bayéma Nébié, Saïdou Gnanou, Adama Zigani, Seydou Mohamed Ouédraogo and 3 more

Abstract read
In one paragraph

Article in European journal of microbiology & immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Souba DiandéProgramme National de Lutte contre la Tuberculose, Ministère de la Santé, Ouagadougou, Burkina Faso.
Gisèle BadoumUniversité Ouaga-I Pr Joseph Ki-Zerbo, Unité de Formation en Sciences de la Santé, Ouagadougou, Burkina Faso.
Adjima CombaryProgramme National de Lutte contre la Tuberculose, Ministère de la Santé, Ouagadougou, Burkina Faso.
Issaka ZombraProgramme National de Lutte contre la Tuberculose, Ministère de la Santé, Ouagadougou, Burkina Faso.
Tandaogo SaouadogoProgramme National de Lutte contre la Tuberculose, Ministère de la Santé, Ouagadougou, Burkina Faso.
Léon T SawadogoProgramme National de Lutte contre la Tuberculose, Ministère de la Santé, Ouagadougou, Burkina Faso.
Bayéma NébiéProgramme National de Lutte contre la Tuberculose, Ministère de la Santé, Ouagadougou, Burkina Faso.
Saïdou GnanouProgramme National de Lutte contre la Tuberculose, Ministère de la Santé, Ouagadougou, Burkina Faso.
Adama ZiganiCentre National de Lutte Antituberculeuse, Ministère de la Santé, Ouagadougou, Burkina Faso.
Seydou Mohamed OuédraogoDirection de la Protection de la Santé et de la Population, Ministère de la Santé, Ouagadougou, Burkina Faso.
Adama DialloProgramme National de Lutte contre la Tuberculose, Ministère de la Santé, Ouagadougou, Burkina Faso.
Seydou KaboréProgramme National de Lutte contre la Tuberculose, Ministère de la Santé, Ouagadougou, Burkina Faso.
Lassana SangaréUniversité Ouaga-I Pr Joseph Ki-Zerbo, Unité de Formation en Sciences de la Santé, Ouagadougou, Burkina Faso.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

settingA survey of the prevalence of drug-resistant tuberculosis (DR-TB) in new and previously treated patients (PTPs) was performed in Burkina Faso from 2016 to 2017.

designIn this cross-sectional survey, a structured questionnaire was administered to eligible smear-positive patients in all 86 diagnostic and treatment centers of the country to collect their socio-demographic characteristics and medical histories. Their sputa were tested using the

resultsOf the 1140 smear-positive patients enrolled, 995 new and 145 PTPs were positive for MTB complex by Xpert. Of these, 2.0% (20/995, 95% confidence interval (CI): 1.1-2.9) of the new cases and 14.5% (95% CI: 14.2-20.2) of the PTPs were resistant to rifampicin; 83% of them has multidrug-resistant tuberculosis (MDR-TB). None were pre-extensively drug-resistant TB (pre-XDR-TB) or XDR-TB. Only the previous treatment was significantly associated with rifampicin resistance,

conclusionSimilar to global trends, rifampicin resistance was significantly higher in patients with prior TB treatment (14.5%) than in naïve patients (2.0%). These percentages are slightly below the global averages, but nonetheless suggest the need for continued vigilance. Extending the use of Xpert testing should strengthen the surveillance of DR-TB in Burkina Faso.

Indexed as

Burkina Fasoprevalencerifampicin resistancesurveytuberculosisXpert MTB/RIF

Identifiers

PMID30967972
PMCPMC6444799

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.