Evidence map›Paper›PMID 30967915›Full record

ArticleInternational journal of preventive medicine2019

Skeletal Muscle Hypertrophy, Insulin-like Growth Factor 1, Myostatin and Follistatin in Healthy and Sarcopenic Elderly Men: The Effect of Whole-body Resistance Training.

Raoof Negaresh, Rouholah Ranjbar, Julien S Baker, Abdolhamid Habibi, Motahare Mokhtarzade, Mohammad Momen Gharibvand, Andrej Fokin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of preventive medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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  11. The Role of Myokines in Liver Diseases.International journal of molecular sciences · 2025
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  20. Effects of resistance training in healthy older people with sarcopenia: a systematic review and meta-analysis of randomized controlled trials.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Raoof NegareshDepartment of Sport Physiology, Shahid Chamran University, Ahvaz, Iran.
Rouholah RanjbarDepartment of Sport Physiology, Shahid Chamran University, Ahvaz, Iran.
Julien S BakerSchool of Science and Sport, University of the West of Scotland, Paisley, Scotland.
Abdolhamid HabibiDepartment of Sport Physiology, Shahid Chamran University, Ahvaz, Iran.
Motahare MokhtarzadeDepartment of Sport Physiology, Shahid Chamran University, Ahvaz, Iran.
Mohammad Momen GharibvandDepartment of Radiology, Jundishapur University of Medical Sciences, Ahvaz, Iran.
Andrej FokinInstitute of Sports Sciences and Innovation, Lithuanian Sports University, Kaunas, Lithuania.
Shahid Chamran University of Ahvaz · IRTarbiat Modares University · IRAhvaz Jundishapur University of Medical Sciences · IRLithuanian Sports University · LTUniversity of the West of Scotland · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia describes the inevitable deterioration in muscle mass and strength that accompanies biological aging. The purpose of this study was to investigate the effects of resistance training (RT) on quadriceps hypertrophy and related biochemistry in sarcopenic and healthy elderly men.

methodsA total of 31 elderly men (55-70 years old) were classified as sarcopenic and nonsarcopenic and were divided into two groups. Both groups participated in a progressive RT program for 8 weeks.

resultsData indicated that the strength in the sarcopenic group increased more than the healthy group (

conclusionsThe findings from this study suggest that RT improves muscle cross-sectional area and biomarker-related muscle loss in both healthy and sarcopenic elderly men. The findings also demonstrate that growth factor profiles at baseline and changes in testosterone levels play an important role in muscle hypertrophy observed in both groups.

Indexed as

Agingfollistatinhypertrophymyostatinresistance trainingsarcopenia

Identifiers

PMID30967915
PMCPMC6425763
OpenAlexW2923586704

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.