Evidence map›Paper›PMID 30967908›Full record

ArticleWorld journal of hepatology2019

Preoperative immunonutrition in patients undergoing liver resection: A prospective randomized trial.

Kylie Russell, Han-Guang Zhang, Lyn K Gillanders, Adam Sjr Bartlett, Helena L Fisk, Philip C Calder, Peter J Swan, Lindsay D Plank

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 6 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 6 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  6. Pooled it
  7. Review
  8. Review
  9. Prehabilitation approaches for gastrointestinal cancer surgery: a narrative review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Nutritional Management of a Liver Transplant Candidate.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Kylie RussellNutrition Services, Auckland City Hospital, Auckland 1023, New Zealand.
Han-Guang ZhangDepartment of Surgery, University of Auckland, Auckland 1023, New Zealand.
Lyn K GillandersNutrition Services, Auckland City Hospital, Auckland 1023, New Zealand.
Adam Sjr BartlettDepartment of Surgery, University of Auckland, Auckland 1023, New Zealand.
Helena L FiskHuman Development and Health, Faculty of Medicine, University of Southampton, Southampton SO171BJ, United Kingdom.
Philip C CalderHuman Development and Health, Faculty of Medicine, University of Southampton, Southampton SO171BJ, United Kingdom.
Peter J SwanDepartment of Surgery, University of Auckland, Auckland 1023, New Zealand.
Lindsay D PlankDepartment of Surgery, University of Auckland, Auckland 1023, New Zealand. l.plank@auckland.ac.nz.
University Hospital Southampton NHS Foundation Trust · GBNIHR Southampton Biomedical Research Centre · GBAuckland City Hospital · NZUniversity of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreoperative supplementation with immunonutrients, including arginine and n-3 fatty acids, has been shown in a number of systematic reviews to reduce infectious complications in patients who have undergone gastrointestinal surgery. Limited information, however, is available on the benefits of nutritional supplementation enriched with arginine and n-3 fatty acids in patients undergoing liver resection.

aimTo evaluate the effects of preoperative nutritional supplementation enriched with arginine and

methodsThirty-four patients undergoing liver resection were randomized to either five days of preoperative Impact

resultsA total of 32 patients (17 IMN and 15 STD) were analysed. All except four patients were SGA class A. The plasma ratio of (eicosapentaenoic acid plus docosahexaenoic acid) to arachidonic acid was higher in IMN patients on the day prior to surgery and POD 1, 3, 5 and 7 (

conclusionIn well-nourished patients undergoing elective liver resection, this study failed to show any benefit of preoperative immunonutrition.

Indexed as

ArginineFish oilInflammationLiver cancerNutritional statusPartial hepatectomy

Identifiers

PMID30967908
PMCPMC6447421
OpenAlexW2924417654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.