ReviewFrontiers in microbiology2019
Cave Actinobacteria as Producers of Bioactive Metabolites.
Review in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
What it found
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Who cites it
67 citing papers in PubMed.
- Biocontrol mechanisms of a karstic cave-derived Streptomyces sp. GCAL-9 bioactive extract against Colletotrichum musae: insights into ergosterol pathway involvement and metabolomic profiling.Archives of microbiology · 2026Article
- Biodiversity and Natural Product Potential of Indonesian Actinomycetes.Journal of microbiology and biotechnology · 2026Review
- Trichostatin Analogues From the Karst Cave Associated Streptomyces sp. DX6D14.Chemistry & biodiversity · 2026Article
- The Incredible Potential of Cave Actinobacteria in Finding New Antimicrobials and Bioactive Compounds.Chemistry & biodiversity · 2026Review
- Ursolic acid methyl ester mitigates aluminum oxide nanoparticle-induced hematobiochemical, immune, and oxidative disturbances and modulates apoptosis-related gene expression in Oreochromis niloticus.Veterinary research communications · 2026Article
- Discovery of natural products that modulate signaling in patient-derived cells.RSC chemical biology · 2026Article
- A novel Streptomyces zaomyceticus metabolite exhibits antifungal activity against Candida albicans in African catfish.BMC veterinary research · 2026Article
- Spatial and functional differentiation of microbial biofilms in a traditional cheese ripening environment.Scientific reports · 2025Article
- Borrelidin M: a new borrelidin derivative obtained from Streptomyces rochei VL-16 exhibited potent antibacterial and antiproliferative properties.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Aerobiology and Environmental Zonation in Gypsum Caves: A Comparative Study of Culturing and NGS Approaches.Microbial ecology · 2025Article
- Revealing the Prokaryotic Microbial Community Structures and their Ecological Potentials in Manjanggul Cave, a Lava Tube on Jeju Island.Current microbiology · 2025Article
- Strategies for Actinobacteria Isolation, Cultivation, and Metabolite Production that Are Biologically Important.ACS omega · 2025Review
- Genomic, Molecular Networking-Based Metabolomic, and Bioactivity Profiling of Actinobacteria from Undisturbed Caves in Pakistan.Applied biochemistry and biotechnology · 2025Article
- A review on bacteria-derived antioxidant metabolites: their production, purification, characterization, potential applications, and limitations.Archives of pharmacal research · 2025Review
- A Review of the Biotechnological Potential of Cave Fungi: A Toolbox for the Future.Journal of fungi (Basel, Switzerland) · 2025Review
- Bioactivity of microbial biofilms in extreme environments.Frontiers in microbiology · 2025Review
- Amplicon Analysis of Dictean Cave Microbial Communities and Essential Oils as a Mild Biocide.Microbes and environments · 2025Article
- Exploring microbial dynamics in ferruginous caves: taxonomic and functional diversity across seasons and cave zones.Frontiers in microbiology · 2025Article
- Exploring the diversity and antimicrobial potential of actinomycetes isolated from different environments in Saudi Arabia: a systematic review.Frontiers in microbiology · 2025Review
- Linear Plasmids in Micrococcus: Insights Into a Common Ancestor and Transfer by Conjugation.Environmental microbiology · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, there is an urgent need for new drugs due to the emergence of drug resistant pathogenic microorganisms and new infectious diseases. Members of phylum Actinobacteria are promising source of bioactive compounds notably antibiotics. The search for such new compounds has shifted to extreme or underexplored environments to increase the possibility of discovery. Cave ecosystems have attracted interest of the research community because of their unique characteristics and the microbiome residing inside including actinobacteria. At the time of writing, 47 species in 30 genera of actinobacteria were reported from cave and cave related habitats. Novel and promising bioactive compounds have been isolated and characterized. This mini-review focuses on the diversity of cultivable actinobacteria in cave and cave-related environments, and their bioactive metabolites from 1999 to 2018.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.