ArticleJournal of perinatology : official journal of the California Perinatal Association2019
Early transpyloric vs gastric feeding in preterm infants: a retrospective cohort study.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04246333 (Feasibility and Safety of Duodenal Feeds in Very Low Birth Weight Infants), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Feasibility and Safety of Duodenal Feeds in Very Low Birth Weight Infants
Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Individualising care in severe bronchopulmonary dysplasia: a series of N-of-1 trials comparing transpyloric and gastric feeding.Archives of disease in childhood. Fetal and neonatal edition · 2020Trial
- [Association between early transpyloric feeding and the risk of bronchopulmonary dysplasia in very preterm/extremely preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Article
- Medical and surgical treatment of gastroesophageal reflux in the neonate.Seminars in perinatology · 2026Review
- Gastroesophageal reflux during postpyloric versus gastric tube feeding in preterm infants with bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2025Observational
- Optimizing Endoscopic Transpyloric Feeding Tube Placement in Low Birth Weight Infants: Practical Insights from Clinical Experience.Medicina (Kaunas, Lithuania) · 2025Article
- Trophic feeding initiation and its predictors in preterm neonates admitted to Neonatal Intensive Care Units: Multicenter study, Addis Ababa.SAGE open medicine · 2025Article
- Transpyloric feeding in severe BPD: a call for prospective trials.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Transpyloric feeding is associated with adverse in-hospital outcomes in infants with severe bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Use of transpyloric feeds in extremely low birth weight infants at risk of severe bronchopulmonary dysplasia-a single center experience.Frontiers in pediatrics · 2024Article
- Bronchopulmonary Dysplasia: Then, Now, and Next.Pediatric allergy, immunology, and pulmonology · 2020Review
- Less invasive surfactant administration reduces incidence of severe intraventricular haemorrage in preterms with respiratory distress syndrome: a cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- [Expert consensus on nutritional management of preterm infants with bronchopulmonary dysplasia].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- Transpyloric feeds and bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2019Article
- Reply to: Transpyloric feeds and bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2019Article
- Early transpyloric feeding: an old wine in a new bottle.Journal of perinatology : official journal of the California Perinatal Association · 2019Article
- Reply to: 'Early transyploric feeding: an old wine in a new bottle'.Journal of perinatology : official journal of the California Perinatal Association · 2019Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeonatal transpyloric feeding (TPF) has not been rigorously studied since the 1980s. Our objective was to evaluate early TPF, defined as TPF initiated within the first week after birth, among preterm infants in the setting of modern neonatal practice. STUDY
designA retrospective cohort study was conducted between 2013 and 2017 for all extremely low birth weight (ELBW) infants born in a tertiary neonatal intensive care unit where early TPF is a common practice. Infants were excluded if they did not receive enteral feeding within the first week after birth or if they died prior to initiation of enteral feeding. The primary outcome was death or bronchopulmonary dysplasia (BPD). The association between early TPF and the primary outcome was assessed using multivariable logistic regression, with adjustment for gestational age, birth weight, and intubation status.
resultThe study sample included 368 ELBW infants. Twenty-seven percent received early TPF. Death or BPD occurred in 58% of infants who received early TPF compared with 67% of infants who received gastric feeding, adjusted odds ratio 0.6, 95% confidence interval 0.3-0.9. Growth and adverse gastrointestinal outcomes did not differ between the two groups.
conclusionEarly TPF is associated with reduced risk of death or BPD among ELBW infants. Further investigation in the form of a randomized controlled trial is required to confirm a causal association between early TPF and improved clinical outcomes.
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