Evidence map›Paper›PMID 30967616›Full record

ArticleLeukemia2019

JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility.

Minhui Lin, Karin Nebral, Christoph G W Gertzen, Ithamar Ganmore, Oskar A Haas, Sanil Bhatia, Ute Fischer, Michaela Kuhlen, Holger Gohlke, Shai Izraeli and 5 more

Abstract readLetter
In one paragraph

Article in Leukemia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. How Genomic and Structural Context Could Shape JAK-STAT Variant Pathogenicity.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Resolving inherited andFrontiers in pediatrics · 2022
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Minhui LinDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Karin NebralChildrens Cancer Research Institute, St. Anna Childrens Hospital, Vienna, Austria.
Christoph G W GertzenInstitute of Pharmaceutical and Medicinal Chemistry, Heinrich-Heine-Universität Düsseldorf, 40225, Düsseldorf, Germany.
Ithamar GanmoreDepartment of Neurology, Sheba Medical Center, Tel Hashomer, Israel.
Oskar A HaasChildrens Cancer Research Institute, St. Anna Childrens Hospital, Vienna, Austria.
Sanil BhatiaDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Ute FischerDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Michaela KuhlenDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.ORCID http://orcid.org/0000-0003-4577-0503
Holger GohlkeInstitute of Pharmaceutical and Medicinal Chemistry, Heinrich-Heine-Universität Düsseldorf, 40225, Düsseldorf, Germany.
Shai IzraeliDivision of Pediatric Hematology and Oncology Schneider Children's Medical Center and Tel Aviv University, Tel Aviv, Israel.
Jan TrkaPediatric Hematology/Oncology, Childhood Leukemia Investigation Prague, Prague, Czech Republic.
Jianda HuFujian Institute of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, 350001, Fuzhou, Fujian, China.
Arndt BorkhardtDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.ORCID http://orcid.org/0000-0002-6121-4737
Julia HauerDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany. Julia.Hauer@uniklinikum-dresden.de.
Franziska AuerDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany. Franziska.Auer@uniklinikum-dresden.de.

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) AU 525/1-1Deutsche Kinderkrebsstiftung (German Childhood Cancer Foundation) 70112951José Carreras Leukämie-Stiftung (Deutsche José Carreras Leukämie-Stiftung) DJCLS 02R/2016
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

B-LymphocytesChildFemaleGenetic Predisposition to DiseaseGerm CellsHumansJanus Kinase 2MalePolymorphism, Single NucleotidePrecursor B-Cell Lymphoblastic Leukemia-LymphomaSignal TransductionJAK2 protein, humanJanus Kinase 2

Identifiers

PMID30967616
PMCPMC6756027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.