Evidence map›Paper›PMID 30967543›Full record

ArticleNature communications2019

Mapping vaccination coverage to explore the effects of delivery mechanisms and inform vaccination strategies.

C Edson Utazi, Julia Thorley, Victor A Alegana, Matthew J Ferrari, Saki Takahashi, C Jessica E Metcalf, Justin Lessler, Felicity T Cutts, Andrew J Tatem

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 2 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 2 syntheses or guidelines pooled it, 130 citations in OpenAlex.

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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

C Edson UtaziWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, SO17 1BJ, UK. c.e.utazi@soton.ac.uk.ORCID http://orcid.org/0000-0002-0534-5310
Julia ThorleyWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, SO17 1BJ, UK.
Victor A AleganaWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, SO17 1BJ, UK.
Matthew J FerrariCenter for Infectious Disease Dynamics, The Pennsylvania State University, State College, PA, 16802, USA.
Saki TakahashiDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, 08544, USA.ORCID http://orcid.org/0000-0001-5413-5507
C Jessica E MetcalfDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, 08544, USA.ORCID http://orcid.org/0000-0003-3166-7521
Justin LesslerDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.
Felicity T CuttsDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
Andrew J TatemWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, SO17 1BJ, UK.
Flowminder Foundation · SEPrinceton University · USUniversity of Southampton · GBJohns Hopkins University · USLondon School of Hygiene & Tropical Medicine · GBPennsylvania State University · US

Funding

Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW G DORSEY, MOSES Robert KAMYA · 2010 to 2026
$29.3M
Scientific and Technical Computing CoreP2CHD047879 · NICHD · PRINCETON UNIVERSITY · PI MASSEY, DOUGLAS S · 2014 to 2018
$2.0M
NIAID NIH HHS U19 AI089674NICHD NIH HHS P2C HD047879Wellcome Trust 211208/Z/18/Z
6 · The paper itself

Abstract

The success of vaccination programs depends largely on the mechanisms used in vaccine delivery. National immunization programs offer childhood vaccines through fixed and outreach services within the health system and often, additional supplementary immunization activities (SIAs) are undertaken to fill gaps and boost coverage. Here, we map predicted coverage at 1 × 1 km spatial resolution in five low- and middle-income countries to identify areas that are under-vaccinated via each delivery method using Demographic and Health Surveys data. We compare estimates of the coverage of the third dose of diphtheria-tetanus-pertussis-containing vaccine (DTP3), which is typically delivered through routine immunization (RI), with those of measles-containing vaccine (MCV) for which SIAs are also undertaken. We find that SIAs have boosted MCV coverage in some places, but not in others, particularly where RI had been deficient, as depicted by DTP coverage. The modelling approaches outlined here can help to guide geographical prioritization and strategy design.

Indexed as

CambodiaChild, PreschoolDatasets as TopicDemocratic Republic of the CongoDemographyDiphtheria-Tetanus-Pertussis VaccineEthiopiaGlobal HealthHumansIncomeInfantInfant, NewbornMass VaccinationMeasles VaccineModels, StatisticalMozambiqueDiphtheria-Tetanus-Pertussis VaccineMeasles Vaccine

Identifiers

PMID30967543
PMCPMC6456602
OpenAlexW2936342662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.