Evidence map›Paper›PMID 30967463›Full record

ArticlemBio2019

JC Polyomavirus Uses Extracellular Vesicles To Infect Target Cells.

Jenna Morris-Love, Gretchen V Gee, Bethany A O'Hara, Benedetta Assetta, Abigail L Atkinson, Aisling S Dugan, Sheila A Haley, Walter J Atwood

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 109 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Nonlytic Egress and Transmission in the Virus World.Annual review of biochemistry · 2025
    Review
  11. Editorial: Viral infection pathogenesis and pathology in nervous system.Frontiers in cellular and infection microbiology · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. The Conserved YPXViruses · 2024
    Article
  18. Article
  19. Review
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jenna Morris-Love *Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA.
Gretchen V Gee *Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA.
Bethany A O'HaraDepartment of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA.
Benedetta AssettaDepartment of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA.
Abigail L AtkinsonDepartment of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA.
Aisling S DuganDepartment of Natural Sciences, Assumption College, Worcester, Massachusetts, USA.
Sheila A HaleyDepartment of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA.
Walter J AtwoodDepartment of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA walter_atwood@brown.edu.ORCID 0000-0002-3763-9073
Brown University · USAssumption College · US

Funding

SYNTHETIC CHEMISTRY COREP01NS065719 · NINDS · BROWN UNIVERSITY · PI GEE, GRETCHEN VOGEL · 2009 to 2018
$12.3M
Virus-Host Cell Interactions in AIDS-Associated PMLR01NS043097 · NINDS · BROWN UNIVERSITY · PI ATWOOD, WALTER J · 2002 to 2020
$6.1M
NINDS NIH HHS P01 NS065719NINDS NIH HHS R01 NS043097
6 · The paper itself

Abstract

The endemic human JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy in immune-suppressed patients. The mechanisms of virus infection

Indexed as

Virus InternalizationCell LineExtracellular VesiclesHumansJC Viruscentral nervous system infectionsextracellular vesiclepolyomavirusprogressive multifocal leukoencephalopathyvirus receptor

Identifiers

PMID30967463
PMCPMC6456752
OpenAlexW2936246848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.