Evidence map›Paper›PMID 30967427›Full record

ArticleDevelopment (Cambridge, England)2019

QuBiT: a quantitative tool for analyzing epithelial tubes reveals unexpected patterns of organization in the

Ran Yang, Eric Li, Yong-Jae Kwon, Madhav Mani, Greg J Beitel

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ran YangDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0001-6104-2691
Eric LiDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-3348-2515
Yong-Jae KwonDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0001-7632-3779
Madhav ManiDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.
Greg J BeitelDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA beitel@northwestern.edu.ORCID 0000-0003-4413-6324
Northwestern University · US

Funding

Tube size control by Src and Yorkie/YAPR01GM108964 · NIGMS · NORTHWESTERN UNIVERSITY · PI BEITEL, GREG J · 2014 to 2017
$1.2M
NIGMS NIH HHS R01 GM108964
6 · The paper itself

Abstract

Biological tubes are essential for animal survival, and their functions are dependent on tube shape. Analyzing the contributions of cell shape and organization to the morphogenesis of small tubes has been hampered by the limitations of existing programs in quantifying cell geometry on highly curved tubular surfaces and calculating tube-specific parameters. We therefore developed QuBiT (Quantitative Tool for Biological Tubes) and used it to analyze morphogenesis of the embryonic

Indexed as

Gene Expression ProfilingGene Expression Regulation, DevelopmentalAdenosine TriphosphateAnimalsBody PatterningCell LineageComputational BiologyCRISPR-Cas SystemsCrosses, GeneticDrosophilaDrosophila ProteinsEpitheliumMembrane ProteinsModels, BiologicalSodium-Potassium-Exchanging ATPaseTracheaAdenosine TriphosphateDrosophila ProteinsMembrane ProteinsSodium-Potassium-Exchanging ATPaseUif protein, DrosophilaDrosophilaEpithelial tubeMorphogenesisMorphometricQuantitative biology

Identifiers

PMID30967427
PMCPMC6602340
OpenAlexW2938784025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.