Evidence map›Paper›PMID 30967415›Full record

ReviewDisease models & mechanisms2019

Modeling congenital kidney diseases in

Alexandria T M Blackburn, Rachel K Miller

Open access · goldAbstract readReview
In one paragraph

Review in Disease models & mechanisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Comparative analysis ofbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Methods for Tattooing Xenopus laevis with a Rotary Tattoo Machine.Journal of visualized experiments : JoVE · 2024
    Article
  7. Review
  8. Article
  9. Animal Models of Human Disease.International journal of molecular sciences · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Model organisms for functional validation in genetic renal disease.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2022
    Article
  16. Article
  17. Article
  18. Adrenergic receptor signaling induced by Klf15, a regulator of regeneration enhancer, promotes kidney reconstruction.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexandria T M BlackburnPediatric Research Center, Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center, Houston, TX 77030, USA.ORCID 0000-0003-2974-0339
Rachel K MillerPediatric Research Center, Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center, Houston, TX 77030, USA Rachel.K.Miller@uth.tmc.edu.ORCID 0000-0002-4214-3347
The University of Texas MD Anderson Cancer Center · US

Funding

Novel Role of Nephron Epithelialization in Nuclear SignalingR01DK115655 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Rachel Katherine Miller · 2019 to 2026
$2.3M
The Role of Planar Cell Polarity Signals in Shaping Kidney TubulesK01DK092320 · NIDDK · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MILLER, RACHEL KATHERINE · 2012 to 2016
$584k
Role of p53 in Kidney Development: Modeling Renal Anomalies of Li-Fraumeni PatientsR03DK118771 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILLER, RACHEL KATHERINE · 2018 to 2019
$231k
NIDDK NIH HHS K01 DK092320NIDDK NIH HHS R01 DK115655NIDDK NIH HHS R03 DK118771
6 · The paper itself

Abstract

Congenital anomalies of the kidney and urinary tract (CAKUT) occur in ∼1/500 live births and are a leading cause of pediatric kidney failure. With an average wait time of 3-5 years for a kidney transplant, the need is high for the development of new strategies aimed at reducing the incidence of CAKUT and preserving renal function. Next-generation sequencing has uncovered a significant number of putative causal genes, but a simple and efficient model system to examine the function of CAKUT genes is needed.

Indexed as

AnimalsCiliaDisease Models, AnimalHumansKidneyKidney DiseasesMammalsXenopus laevisCAKUTCRISPRKidneyNephronNephronophthisisPKDXenopus

Identifiers

PMID30967415
PMCPMC6505484
OpenAlexW2939037766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.