Trial reportBMJ open2019
A guided and unguided internet- and mobile-based intervention for chronic pain: health economic evaluation alongside a randomised controlled trial.
Trial report in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effects of Prehabilitation With Advanced Technologies in Patients With Musculoskeletal Diseases Waiting for Surgery: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Psychological therapies delivered remotely for the management of chronic pain (excluding headache) in adults.The Cochrane database of systematic reviews · 2023Pooled it
- Economic Evaluations of Digital Health Interventions for the Management of Musculoskeletal Disorders: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2023Pooled it
- Digital Health Interventions for Musculoskeletal Pain Conditions: Systematic Review and Meta-analysis of Randomized Controlled Trials.Journal of medical Internet research · 2022Pooled it
- Embrace Pain-A Randomized Controlled Trial of Online Acceptance and Commitment Therapy for Painful Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors.Psycho-oncology · 2026Trial
- Delivery Model Matters for Digital Interventions in Pain Self-Management: Mixed Methods Study.Journal of medical Internet research · 2026Trial
- Digital Behavioral Therapy Improves Outcome in Patients With Axial Spondyloarthritis and Persistent Pain: A Randomized Controlled Trial.Arthritis care & research · 2026Trial
- Health economic evaluation of a randomized controlled trial (EMBLA study), an internet-based treatment for provoked vulvodynia.Scientific reports · 2023Trial
- Trial
- A Web-Based Acceptance-Facilitating Intervention for Identifying Patients' Acceptance, Uptake, and Adherence of Internet- and Mobile-Based Pain Interventions: Randomized Controlled Trial.Journal of medical Internet research · 2018Trial
- Cost savings and quality-of-life gains associated with the use of an AI-powered digital tool for self-management of chronic pain based on a multicenter cohort study.Pain medicine (Malden, Mass.) · 2026Article
- Cost-effectiveness analysis of active day patient treatment, an interdisciplinary pain self-management program.Pain reports · 2025Article
- Exploring Psychotherapists' Attitudes on Internet- and Mobile-Based Interventions in Germany: Thematic Analysis.JMIR formative research · 2024Article
- Efficacy and mechanisms of mobile application-delivered Acceptance and Commitment Therapy for posttraumatic stress disorder in China: Study protocol for a randomized controlled trial.Internet interventions · 2022Article
- Online Acceptance and Commitment Therapy (ACT) interventions for chronic pain: A systematic literature review.Internet interventions · 2021Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aims at evaluating the cost-effectiveness and cost-utility of a guided and unguided internet-based intervention for chronic pain patients (ACTonPain
designThis is a health economic evaluation alongside a three-arm randomised controlled trial from a societal perspective. Assessments were conducted at baseline, 9 weeks and 6 months after randomisation.
settingParticipants were recruited through online and offline strategies and in collaboration with a health insurance company.
participants302 adults (≥18 years, pain for at least 6 months) were randomly allocated to one of the three groups (ACTonPain
interventionsACTonPain consists of seven modules and is based on Acceptance and Commitment Therapy. ACTonPain PRIMARY AND SECONDARY OUTCOME MEASURES: Main outcomes of the cost-effectiveness and the cost-utility analyses were meaningful change in pain interference (treatment response) and quality-adjusted life years (QALYs), respectively. Economic evaluation estimates were the incremental cost-effectiveness and cost-utility ratio (ICER/ICUR).
resultsAt 6-month follow-up, treatment response and QALYs were highest in ACTonPain
conclusionsDepending on society's willingness-to-pay, ACTonPain is a potentially cost-effective adjunct to established pain treatment. ACTonPain TRIAL REGISTRATION NUMBER: DRKS00006183.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.