Trial reportBMC musculoskeletal disorders2019
The effects of a home-based exercise intervention on elderly patients with knee osteoarthritis: a quasi-experimental study.
Trial report in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 5 syntheses or guidelines pooled it, 167 citations in OpenAlex.
- Antithrombotic prophylaxis following total knee arthroplasty: a level I Bayesian network meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Pooled it
- Efficacy of home-based exercise in the treatment of pain and disability at the hip and knee in patients with osteoarthritis: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2024Pooled it
- Effectiveness of home-based exercise interventions on pain, physical function and quality of life in individuals with knee osteoarthritis: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- A recommended exercise program appropriate for patients with knee osteoarthritis: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- Benefits and Mechanisms of Exercise Training for Knee Osteoarthritis.Frontiers in physiology · 2021Pooled it
- A Telemedicine App for Nonrigid Facial Rehabilitation Training Enhanced by Efficient Fully Convolutional Neural Network With Residual Network (EffiFCNN-ResNet) to Improve Accessibility for Patients With Nasopharyngeal Carcinoma Cancer: Randomized Controlled Trial.JMIR mHealth and uHealth · 2026Trial
- Effectiveness of genicular nerve block on pain and disability in chronic knee osteoarthritis: a randomized double blinded placebo controlled trial.Clinical rheumatology · 2026Trial
- Swedish massage versus hip strengthening exercises for pain and function in older adults with knee osteoarthritis: a randomized controlled trial.Aging clinical and experimental research · 2026Trial
- Effects of a Computer Vision-Based Exercise Application for People With Knee Osteoarthritis: Randomized Controlled Trial.JMIR mHealth and uHealth · 2025Trial
- Active Neurodynamic Technique at Home in Patients with Knee Osteoarthritis: An Open Single Arm Clinical Trial.Medicina (Kaunas, Lithuania) · 2024Trial
- Saccharomyces boulardii improves clinical and paraclinical indices in overweight/obese knee osteoarthritis patients: a randomized triple-blind placebo-controlled trial.European journal of nutrition · 2024Trial
- Effects of Self-management Program as Adjunctive to Usual Rehabilitation Exercise on Pain and Functional Outcomes in Knee Osteoarthritis: A Randomized Controlled Trial.Journal of research in health sciences · 2023Trial
- The effects on pain, physical function, and quality of life of quadriceps strengthening exercises combined with Baduanjin qigong in older adults with knee osteoarthritis: a quasi-experimental study.BMC musculoskeletal disorders · 2021Trial
- The effect of transtheoretical model-lead intervention for knee osteoarthritis in older adults: a cluster randomized trial.Arthritis research & therapy · 2020Trial
- Application of Deep Learning-Based Markerless Pose Estimation in a 3D Exergame System for Knee Osteoarthritis Exercise Management: Development and Preliminary Evaluation.Sensors (Basel, Switzerland) · 2026Article
- Osteoarthritis: Epidemiology, Diagnosis, and Treatment.MedComm · 2026Review
- Network-guided symptom targets in maintenance hemodialysis using in silico interventions: a multicenter cross-sectional study.BMC nephrology · 2026Observational
- Loss of mechanical stress induces synovitis, fibrosis and articular cartilage degeneration via distinct synovial cell subsets.Scientific reports · 2026Article
- Effect of Rehabilitation Program for Muscle Strength, Balance, and Gait Retraining with Visual Feedback in Older Women with and Without Knee Osteoarthritis: Clinical Trial.Journal of personalized medicine · 2025Article
- The Role of Home-Based Exercise in Managing Common Musculoskeletal Disorders: A Narrative Review.Journal of functional morphology and kinesiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundKnee osteoarthritis (KOA) is common in elderly people, causes pain, loss of physical functioning, and disability. This was a two-arm, superiority, quasi-experimental trial. The aim of this study was to evaluate the effectiveness of a home-based exercise intervention (HBEI) to reduce KOA symptoms and improve the physical functioning of elderly patients.
methodsA total of 171 elderly patients (60 years of age or older) with KOA were recruited from four community centers. Patients from two community centers were randomly assigned to the intervention group (IG) and the other two centers were randomly assigned to the control group (CG). Participants in the IG received a 12-week HBEI (including four 2-h sessions supervised by a physiotherapist and fortnightly telephone support) combined with health education, while patients in the CG only received health education. The participants and physiotherapists were aware of the group assignment and alternative treatment components, but the study's hypotheses were not disclosed to the participants. Pain intensity, joint stiffness, lower-limb muscle strength, balance, mobility, and quality of life were measured before and after the intervention by the same blinded assessor.
resultsA total of 171 patients (IG: n = 84, CG: n = 87) were enrolled. Data were obtained from 141 patients with an average age of 68 (range, 60-86 years) who completed the 12-week study (IG: n = 71, CG: n = 70). No significant group differences were found in any outcome measures at baseline. At week 12, the pretest/posttest changes 3significant between-group differences in decreases in pain intensity (- 1.60 (CI, - 2.75 to - 0.58)) and stiffness (- 0.79 (CI, - 1.37 to - 0.21)), with the IG exhibiting significantly larger improvements on both measures than the CG. The IG also showed significantly greater improvements on all the secondary outcomes than the CG did.
conclusionsHBEI may be effective for relieving KOA symptoms, increasing the physical functioning, and improving quality of life in community-dwelling KOA elderly patients. A large randomized controlled trial with long-term follow-up is needed to confirm these findings.
trial registrationChinese Clinical Trails Registry number ChiCTR1800017026 (retrospectively registered). Registered 9 July 2018.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.