ArticleBMC musculoskeletal disorders2019
Relationship of joint hypermobility with low Back pain and lumbar spine osteoarthritis.
Article in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Generalized Joint Hypermobility in Adults: A Systematic Review With Meta-Analysis to Identify Data-Driven Cut-offs Using the Beighton Score.Arthritis care & research · 2026Pooled it
- Evaluation of lumbar segmental motion using ultrasound imaging following common joint mobilization techniques.The Journal of manual & manipulative therapy · 2025Trial
- Generalized joint hypermobility and neck pain: Prevalence and functional correlates from a community-based sample.Clinical biomechanics (Bristol, Avon) · 2026Article
- The Impact of Telehealth Use Experience on Recruitment of Underserved Populations Into a Telehealth-Delivered Mindfulness-Based Trial for Patients With Chronic Low Back Pain: Cross-Sectional Survey.JMIR mHealth and uHealth · 2026Article
- Generalized Joint Hypermobility in Adolescent Idiopathic Scoliosis: Greater Curve Flexibility, Larger Thoracic Kyphosis, but Higher Complication Risk.Orthopaedic surgery · 2026Article
- [Hypermobility-Importance in rheumatology].Zeitschrift fur Rheumatologie · 2025Review
- Associations between flexibility, stretching habits, and spine injuries in professional golfers: a nationwide, cross-sectional study.Journal of orthopaedic surgery and research · 2025Article
- Characteristics of spinal injury in professional golfers in South Korea: a nationwide cross-sectional study.BMJ open · 2025Article
- Hypermobility Among Adolescents and the Association With Spinal Deformities: A Large Cross-Sectional Study.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2024Article
- A Zebrafish Mutant in the Extracellular Matrix Protein GeneAnimals : an open access journal from MDPI · 2023Article
- Symptomatic Joint Hypermobility Is Associated with Low Back Pain: A National Adolescents Cohort Study.Journal of clinical medicine · 2022Article
- Kinesiological Treatment of Early Spine Osteoarthritis in a Motorcyclist.International journal of environmental research and public health · 2022Article
- Chronic Low Back Pain Occurring in Association With Hypermobility Spectrum Disorder and Ehlers-Danlos Syndrome.International journal of spine surgery · 2021Article
- Distinguishing chronic low back pain in young adults with mild to moderate pain and disability using trunk compliance.Scientific reports · 2021Article
- Pelvic Girdle Pain, Hypermobility Spectrum Disorder and Hypermobility-Type Ehlers-Danlos Syndrome: A Narrative Literature Review.Journal of clinical medicine · 2020Review
- Joint hypermobility is not positively associated with prevalent multiple joint osteoarthritis: a cross-sectional study of older adults.BMC musculoskeletal disorders · 2019Article
- Association between general joint hypermobility and knee, hip, and lumbar spine osteoarthritis by race: a cross-sectional study.Arthritis research & therapy · 2018Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundChronic low back pain (cLBP) affects millions of Americans and costs billions. Studies suggest a link between cLBP and joint hypermobility.
methodsWe conducted cross-sectional primary analyses of joint hypermobility and cLBP, lumbar spine osteoarthritis (OA), and lumbar facet joint OA (FOA) in 3 large studies-the Generalized Osteoarthritis Study, Genetics of Generalized Osteoarthritis Study, and Johnston County Osteoarthritis Project (total n = 5072). Associations of joint hypermobility and Beighton trunk flexion with cLBP and lumbar OA were estimated using separate adjusted logistic regression models. Adjusted pooled odds ratios (pORs) and 95% confidence intervals (CIs) were then summarized-using random effect univariate, multivariate crude, and adjusted models-and heterogeneity was determined (I
resultsIn univariate models, hypermobility was associated with symptomatic FOA (pOR = 0.64 [95% CI 0.44, 0.93]) but this result was not found in the multivariate models. In multivariate adjusted models, hypermobility was not significantly associated with cLBP and lumbar OA, but trunk flexion was inversely associated with cLBP (pOR = 0.40 [95% 0.26, 0.62]), spine OA (pOR = 0.66 [95% CI 0.50, 0.87]), symptomatic spine OA (pOR = 0.39 [95% CI 0.28, 0.53]), and symptomatic FOA (pOR = 0.53 [95% CI 0.37, 0.77]). Generally, between-study heterogeneity was moderate-high.
conclusionsHypermobility was not associated with cLBP or lumbar OA. The inverse association of trunk flexion with cLBP and lumbar OA may indicate a role for a flexible spine in avoiding or managing these conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.