ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2019
Interaction of viral pathogen with porin channels on the outer membrane of insect bacterial symbionts mediates their joint transovarial transmission.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 24 citations in OpenAlex.
- Reoviruses hijack the SMARCB1-MYC transcriptional regulation complex to activate autophagy for persistent viral infection in leafhopper vector.PLoS pathogens · 2025Article
- An insect symbiotic virus promotes the transmission of a phytoarbovirus via inhibiting E3 ubiquitin ligase Sina.PLoS pathogens · 2025Article
- Insect ribosome-rescuer Pelo-Hbs1 complex on sperm surface mediates paternal arbovirus transmission.Nature communications · 2024Article
- Single-cell RNA-seq reveals distinct metabolic "microniches" and close host-symbiont interactions in deep-sea chemosynthetic tubeworm.Science advances · 2024Article
- Facultatively intrabacterial localization of a planthopper endosymbiont as an adaptation to its vertical transmission.mSystems · 2024Article
- Diversity and functional characteristics of culturable bacterial endosymbionts from cassava whitefly biotype Asia II-5,3 Biotech · 2024Article
- Detection ofFrontiers in plant science · 2024Article
- Review
- Autophagy mediates a direct synergistic interaction during co-transmission of two distinct arboviruses by insect vectors.Science China. Life sciences · 2023Article
- Diversity and Dynamics of Bacterial Communities in the Digestive and Excretory Systems across the Life Cycle of Leafhopper,Insects · 2023Article
- Arboviruses and symbiotic viruses cooperatively hijack insect sperm-specific proteins for paternal transmission.Nature communications · 2023Article
- A Review of Vector-Borne Rice Viruses.Viruses · 2022Review
- Roles of Bacterial Symbionts in Transmission of Plant Virus by Hemipteran Vectors.Frontiers in microbiology · 2022Review
- Insect Bacterial Symbiont-Mediated Vitellogenin Uptake into Oocytes To Support Egg Development.mBio · 2020Article
- Exploiting insect-specific viruses as a novel strategy to control vector-borne disease.Current opinion in insect science · 2020Review
- A Neuron-Specific Antiviral Mechanism Modulates the Persistent Infection of Rice Rhabdoviruses in Leafhopper Vectors.Frontiers in microbiology · 2020Article
- Overview: biotic signalling for smart pest management.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many hemipteran insects that can transmit plant viruses in a persistent and transovarial manner are generally associated with a common obligate bacterial symbiont Sulcia and its β-proteobacterial partner. Rice dwarf virus (RDV), a plant reovirus, can bind to the envelope of Sulcia through direct interaction of the viral minor outer capsid protein P2 with the bacterial outer membrane protein, allowing the virus to exploit the ancient oocyte entry path of Sulcia in rice leafhopper vectors. Here, we show that RDV can hitchhike with both Sulcia and its β-proteobacterial partner Nasuia to ensure their simultaneous transovarial transmission. Interestingly, RDV can move through the outer envelope of Nasuia and reside in the periplasmic space, which is mediated by the specific interaction of the viral major outer capsid protein P8 and the porin channel on the bacterial outer envelope. Nasuia porin-specific antibody efficiently interferes with the binding between RDV and the Nasuia envelope, thus strongly preventing viral transmission to insect offspring. Thus, RDV has evolved different strategies to exploit the ancient oocyte entry paths used by two obligate bacterial symbionts in rice leafhoppers. Our results thus reveal that RDV has formed complex, cooperative interactions with both Sulcia and Nasuia during their joint transovarial transmission. This article is part of the theme issue 'Biotic signalling sheds light on smart pest management'.
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