Evidence map›Paper›PMID 30966500›Full record

ArticlePolymers2018

Chitosan Composites Synthesized Using Acetic Acid and Tetraethylorthosilicate Respond Differently to Methylene Blue Adsorption.

Thomas Y A Essel, Albert Koomson, Marie-Pearl O Seniagya, Grace P Cobbold, Samuel K Kwofie, Bernard O Asimeng, Patrick K Arthur, Gordon Awandare, Elvis K Tiburu

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Thomas Y A EsselDepartment of Biomedical Engineering, University of Ghana, P.O. Box LG 25, Legon, Ghana. tyaessel@st.ug.edu.gh.
Albert KoomsonDepartment of Biomedical Engineering, University of Ghana, P.O. Box LG 25, Legon, Ghana. albert.koomson@stu.ucc.edu.gh.
Marie-Pearl O SeniagyaDepartment of Biomedical Engineering, University of Ghana, P.O. Box LG 25, Legon, Ghana. moseniagya@st.ug.edu.gh.
Grace P CobboldDepartment of Biomedical Engineering, University of Ghana, P.O. Box LG 25, Legon, Ghana. gracecobbold2016@gmail.com.
Samuel K KwofieDepartment of Biomedical Engineering, University of Ghana, P.O. Box LG 25, Legon, Ghana. skwofie2000@gmail.com.
Bernard O AsimengDepartment of Biomedical Engineering, University of Ghana, P.O. Box LG 25, Legon, Ghana. boasimeng@ug.edu.gh.
Patrick K ArthurDepartment of Biochemistry, Cell and Molecular Biology, University of Ghana, P.O. Box LG 25, Legon, Ghana. parthur14@gmail.com.
Gordon AwandareDepartment of Biochemistry, Cell and Molecular Biology, University of Ghana, P.O. Box LG 25, Legon, Ghana. gawandare@ug.edu.gh.
Elvis K TiburuDepartment of Biomedical Engineering, University of Ghana, P.O. Box LG 25, Legon, Ghana. etiburu@ug.edu.gh.
University of Ghana · GH

Funding

Wellcome Trust
6 · The paper itself

Abstract

The sol-gel and cross-linking processes have been used by researchers to synthesize silica-based nanostructures and optimize their size and morphology by changing either the material or the synthesis conditions. However, the influence of the silica nanostructures on the overall physicochemical and mechanistic properties of organic biopolymers such as chitosan has received limited attention. The present study used a one-step synthetic method to obtain chitosan composites to monitor the uptake and release of a basic cationic dye (methylene blue) at two different pH values. Firstly, the composites were synthesized and characterized by Fourier Transform Infrared Spectroscopy (FTIR) and X-ray Diffraction (XRD) to ascertain their chemical identity. Adsorption studies were conducted suing methylene blue and these studies revealed that Acetic Acid-Chitosan (AA-CHI), Tetraethylorthosilicate-Chitosan (TEOS-CHI), Acetic Acid-Tetraethylorthosilicate-Chitosan (AA-TEOS-CHI), and Acetic Acid-Chitosan-Tetraethylorthosilicate (AA-CHI-TEOS) had comparatively lower percentage adsorbances in acidic media after 40 h, with AA-CHI adsorbing most of the methylene blue dye. In contrast, these materials recorded higher percentage adsorbances of methylene blue in the basic media. The release profiles of these composites were fitted with an exponential model. The R-squared values obtained indicated that the AA-CHI at pH ~ 2.6 and AA-TEOS-CHI at pH ~ 7.2 of methylene blue had steady and consistent release profiles. The release mechanisms were analyzed using Korsmeyer-Peppas and Hixson-Crowell models. It was deduced that the release profiles of the majority of the synthesized chitosan beads were influenced by the conformational or surface area changes of the methylene blue. This was justified by the higher correlation coefficient or Pearson's

Indexed as

chitosancross-linkingFTIRinterpenetratingmethylene bluemodellingTEOSXRD

Identifiers

PMID30966500
PMCPMC6415437
OpenAlexW2801781761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.