Evidence map›Paper›PMID 30966418›Full record

ArticlePolymers2018

Investigation on the Nanomechanics of Liposome Adsorption on Titanium Alloys: Temperature and Loading Effects.

Yiqin Duan, Yuhong Liu, Jinjin Li, Hongdong Wang, Shizhu Wen

Abstract read
In one paragraph

Article in Polymers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yiqin DuanState Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China. duanyiqin91@163.com.
Yuhong LiuState Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China. liuyuhong@tsinghua.edu.cn.
Jinjin LiState Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China. lijinjin@mail.tsinghua.edu.cn.
Hongdong WangState Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China. sckler@163.com.
Shizhu WenState Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China. dpiwsz@mail.tsinghua.edu.cn.

Funding

National Natural Science Foundation of Chin 51522504National Natural Science Foundation of China 51527901National Natural Science Foundation of China 51775295
6 · The paper itself

Abstract

The mechanical properties of liposomes, determined by the lipid phase state at ambient temperature, have a close relationship with their physiological activities. Here, atomic force microscopy (AFM) was used to produce images and perform force measurements on titanium alloys at two adsorbed temperatures. The mechanical properties were evaluated under repeated loading and unloading, suggesting a better reversibility and resistance of gel phase liposomes. The liquid phase liposomes were irreversibly damaged during the first approach while the gel phase liposomes could bear more iterations, resulting from water flow reversibly going across the membranes. The statistical data offered strong evidence that the lipid membranes in the gel phase are robust enough to resist the tip penetration, mainly due to their orderly organization and strong hydrophobic interactions between lipid molecules. This work regarding the mechanical properties of liposomes with different phases provides guidance for future clinical applications, such as artificial joints.

Indexed as

AFMgel phaseliposomenanomechanicstitanium alloy

Identifiers

PMID30966418
PMCPMC6415199

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.