Evidence map›Paper›PMID 30966320›Full record

ReviewPolymers2018

3D Printing and Electrospinning of Composite Hydrogels for Cartilage and Bone Tissue Engineering.

Arianna De Mori, Marta Peña Fernández, Gordon Blunn, Gianluca Tozzi, Marta Roldo

Abstract readReview
In one paragraph

Review in Polymers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Review
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  10. Standardised Matrices for Stem Cells.Advances in experimental medicine and biology · 2025
    Review
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Arianna De MoriSchool of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2DT, UK. arianna.demori@port.ac.uk.
Marta Peña FernándezZeiss Global Centre, School of Engineering, University of Portsmouth, Portsmouth PO1 3DJ, UK. marta.pena-fernandez@port.ac.uk.
Gordon BlunnSchool of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2DT, UK. gordon.blunn@port.ac.uk.
Gianluca TozziZeiss Global Centre, School of Engineering, University of Portsmouth, Portsmouth PO1 3DJ, UK. gianluca.tozzi@port.ac.uk.ORCID 0000-0002-3172-5720
Marta RoldoSchool of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2DT, UK. marta.roldo@port.ac.uk.ORCID 0000-0003-2242-7761

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Injuries of bone and cartilage constitute important health issues costing the National Health Service billions of pounds annually, in the UK only. Moreover, these damages can become cause of disability and loss of function for the patients with associated social costs and diminished quality of life. The biomechanical properties of these two tissues are massively different from each other and they are not uniform within the same tissue due to the specific anatomic location and function. In this perspective, tissue engineering (TE) has emerged as a promising approach to address the complexities associated with bone and cartilage regeneration. Tissue engineering aims at developing temporary three-dimensional multicomponent constructs to promote the natural healing process. Biomaterials, such as hydrogels, are currently extensively studied for their ability to reproduce both the ideal 3D extracellular environment for tissue growth and to have adequate mechanical properties for load bearing. This review will focus on the use of two manufacturing techniques, namely electrospinning and 3D printing, that present promise in the fabrication of complex composite gels for cartilage and bone tissue engineering applications.

Indexed as

3D printingbonecartilagecomposite hydrogelselectrospinning

Identifiers

PMID30966320
PMCPMC6414880

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.