Evidence map›Paper›PMID 30965987›Full record

ReviewPolymers2017

Preparation, Characterization and Application of Polysaccharide-Based Metallic Nanoparticles: A Review.

Cong Wang, Xudong Gao, Zhongqin Chen, Yue Chen, Haixia Chen

Abstract readReview
In one paragraph

Review in Polymers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Influence of Agaricus blazei Murill polysaccharides on synthesis, stabilization, acute toxicity and antifungal activity of copper (II) oxide nanoparticles.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
  11. Materials (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Selenium Bio-Nanocomposite Based onBioengineering (Basel, Switzerland) · 2023
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cong WangTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China. 1015213012@tju.edu.cn.ORCID 0000-0002-2724-9274
Xudong GaoTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China. xdgao@tju.edu.cn.ORCID 0000-0002-1284-9162
Zhongqin ChenTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China. chenzhongqin@tju.edu.cn.ORCID 0000-0002-2249-7092
Yue ChenTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China. chenyue0126@tju.edu.cn.
Haixia ChenTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China. chenhx@tju.edu.cn.ORCID 0000-0002-2596-9622

Funding

National High Technology Research and Development Program ("863" Program) of China SS2013AA100207National Natural Science Foundation of China NSFC 31371879
6 · The paper itself

Abstract

Polysaccharides are natural biopolymers that have been recognized to be the most promising hosts for the synthesis of metallic nanoparticles (MNPs) because of their outstanding biocompatible and biodegradable properties. Polysaccharides are diverse in size and molecular chains, making them suitable for the reduction and stabilization of MNPs. Considerable research has been directed toward investigating polysaccharide-based metallic nanoparticles (PMNPs) through host⁻guest strategy. In this review, approaches of preparation, including top-down and bottom-up approaches, are presented and compared. Different characterization techniques such as scanning electron microscopy, transmission electron microscopy, dynamic light scattering, UV-visible spectroscopy, Fourier-transform infrared spectroscopy, X-ray diffraction and small-angle X-ray scattering are discussed in detail. Besides, the applications of PMNPs in the field of wound healing, targeted delivery, biosensing, catalysis and agents with antimicrobial, antiviral and anticancer capabilities are specifically highlighted. The controversial toxicological effects of PMNPs are also discussed. This review can provide significant insights into the utilization of polysaccharides as the hosts to synthesize MPNs and facilitate their further development in synthesis approaches, characterization techniques as well as potential applications.

Indexed as

applicationbiopolymershost–guest strategypolysaccharide-based metallic nanoparticlespolysaccharidespreparation and characterizationtoxicity evaluation

Identifiers

PMID30965987
PMCPMC6418682

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.