ReviewPolymers2017
Hydrogels for Cartilage Regeneration, from Polysaccharides to Hybrids.
Review in Polymers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed.
- Innovative Hydroxyapatite-Hydrogel Composites for Cartilage Regeneration.Gels (Basel, Switzerland) · 2026Review
- Tissue engineering of articular cartilage using nasal chondrocytes on alginate-chitosan-based composite scaffolds.Cell and tissue banking · 2026Article
- Advanced Hydrogels in Fibrocartilage Regeneration of the Glenoid Labrum.Gels (Basel, Switzerland) · 2025Review
- Interlacing biology and engineering: An introduction to textiles and their application in tissue engineering.Materials today. Bio · 2025Review
- Pharmacological Behavior of Propylene Glycol/Polyvinyl Alcohol Hydrogel Incorporating Indomethacin Nanocrystals in the Skin.Gels (Basel, Switzerland) · 2025Article
- Preparation and Properties of Glycerohydrogels Based on Silicon Tetraglycerolate, Chitosan Hydrochloride and Glucomannan.Gels (Basel, Switzerland) · 2025Article
- An Adhesive Hydrogel Technology for Enhanced Cartilage Repair: A Preliminary Proof of Concept.Gels (Basel, Switzerland) · 2024Article
- Cartilage Repair: Promise of Adhesive Orthopedic Hydrogels.International journal of molecular sciences · 2024Review
- Silica-Reinforced AMP-Calcium Alginate Beads for Efficient and Selective Removal of Cesium from a Strong Acidic Medium.ACS omega · 2024Article
- Article
- Fabrication of Sodium Trimetaphosphate-Based PEDOT:PSS Conductive Hydrogels.Gels (Basel, Switzerland) · 2024Article
- 3D printed osteochondral scaffolds: design strategies, present applications and future perspectives.Frontiers in bioengineering and biotechnology · 2024Review
- Advanced Hydrogel-Based Strategies for Enhanced Bone and Cartilage Regeneration: A Comprehensive Review.Gels (Basel, Switzerland) · 2023Review
- The Effect of Chitosan on Physicochemical Properties of Whey Protein Isolate Scaffolds for Tissue Engineering Applications.Polymers · 2023Article
- Hyalofast Cartilage Repair Surgery with a Full Load-Bearing Rehabilitation Program One Day after Operation Reduces the Time for Professional Athletes to Return to Play.Medicina (Kaunas, Lithuania) · 2023Article
- Review
- Women's contribution to stem cell research for osteoarthritis: an opinion paper.Frontiers in cell and developmental biology · 2023Review
- Nanofiber scaffolds based on extracellular matrix for articular cartilage engineering: A perspective.Nanotheranostics · 2023Review
- 3D Bioprinting of Smart Oxygen-Releasing Cartilage Scaffolds.Journal of functional biomaterials · 2022Review
- Application of Nano-Inspired Scaffolds-Based Biopolymer Hydrogel for Bone and Periodontal Tissue Regeneration.Polymers · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aims of this paper are: (1) to review the current state of the art in the field of cartilage substitution and regeneration; (2) to examine the patented biomaterials being used in preclinical and clinical stages; (3) to explore the potential of polymeric hydrogels for these applications and the reasons that hinder their clinical success. The studies about hydrogels used as potential biomaterials selected for this review are divided into the two major trends in tissue engineering: (1) the use of cell-free biomaterials; and (2) the use of cell seeded biomaterials. Preparation techniques and resulting hydrogel properties are also reviewed. More recent proposals, based on the combination of different polymers and the hybridization process to improve the properties of these materials, are also reviewed. The combination of elements such as scaffolds (cellular solids), matrices (hydrogel-based), growth factors and mechanical stimuli is needed to optimize properties of the required materials in order to facilitate tissue formation, cartilage regeneration and final clinical application. Polymer combinations and hybrids are the most promising materials for this application. Hybrid scaffolds may maximize cell growth and local tissue integration by forming cartilage-like tissue with biomimetic features.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.