Evidence map›Paper›PMID 30965745›Full record

ArticlePolymers2017

Topological Models for Open-Knotted Protein Chains Using the Concepts of Knotoids and Bonded Knotoids.

Dimos Goundaroulis, Neslihan Gügümcü, Sofia Lambropoulou, Julien Dorier, Andrzej Stasiak, Louis Kauffman

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 60 citations in OpenAlex.

  1. Theta-curves in proteins.Protein science : a publication of the Protein Society · 2024
    Article
  2. Evolutionary Khovanov homology.AIMS mathematics · 2024
    Article
  3. Article
  4. Article
  5. Knot polynomials of open and closed curves.Proceedings. Mathematical, physical, and engineering sciences · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Dimos GoundaroulisCenter for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland. dimoklis.gkountaroulis@unil.ch.ORCID 0000-0002-2874-6272
Neslihan GügümcüDepartment of Mathematics, National Technical University of Athens, Zografou Campus, 15780 Athens, Greece. nesli@central.ntua.gr.
Sofia LambropoulouDepartment of Mathematics, National Technical University of Athens, Zografou Campus, 15780 Athens, Greece. sofia@math.ntua.gr.
Julien DorierCenter for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland. julien.dorier@unil.ch.ORCID 0000-0002-6717-2451
Andrzej StasiakCenter for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland. Andrzej.Stasiak@unil.ch.ORCID 0000-0002-0398-1989
Louis KauffmanDepartment of Mathematics, Statistics and Computer Science, University of Illinois at Chicago, Chicago, IL 60607-7045, USA. kauffman@uic.edu.ORCID 0000-0003-4135-8685
SIB Swiss Institute of Bioinformatics · CHNational Technical University of Athens · GRUniversity of Illinois Chicago · US

Funding

Leverhulme Trust RP2013-K-017Swiss National Science Foundation 31003A-138267
6 · The paper itself

Abstract

In this paper we introduce a method that offers a detailed overview of the entanglement of an open protein chain. Further, we present a purely topological model for classifying open protein chains by also taking into account any bridge involving the backbone. To this end, we implemented the concepts of planar knotoids and bonded knotoids. We show that the planar knotoids technique provides more refined information regarding the knottedness of a protein when compared to established methods in the literature. Moreover, we demonstrate that our topological model for bonded proteins is robust enough to distinguish all types of lassos in proteins.

Indexed as

knotoidsknot theoryprotein knotstopology

Identifiers

PMID30965745
PMCPMC6418563
OpenAlexW2754103563

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.