ArticleCell and tissue research1986
Relationship between the organization of actin bundles and vinculin plaques.
Article in Cell and tissue research, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 8 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The temporal pattern of the formation and dissolution of vinculin patches during experimental manipulation of the state of actin within the cell was studied. Cytochalasin D-induced retraction and disappearance of stress fibers is followed, with a brief delay, by the dissolution of vinculin-containing patches and the coordinated redistribution of both actin and vinculin into newly formed amorphous aggregates or foci. Recovery from cytochalasin treatment begins with a transformation of these foci into doughnut-shaped assemblies in which actin and vinculin are precisely co-localized. The emergence and growth of filament bundles is paralleled by the appearance of faint vinculin patches that gradually increase in size in parallel with the stress fibers. If stress fibers are stabilized by microinjected rhodamine-phalloidin against stimuli that normally induce a coordinated redistribution of actin and vinculin, also the vinculin patches persist. These observations indicate that treatments influencing the state of actin in the cell have corresponding effects on the stability of vinculin patches and suggest a strong interdependency of actin and vinculin organization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.