Evidence map›Paper›PMID 30965560›Full record

ArticleSensors (Basel, Switzerland)2019

Use of Surface-Enhanced Raman Scattering (SERS) Probes to Detect Fatty Acid Receptor Activity in a Microfluidic Device.

Han Zhang, Wei Zhang, Lifu Xiao, Yan Liu, Timothy A Gilbertson, Anhong Zhou

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Spatiotemporal dynamic monitoring of fatty acid-receptor interaction on single living cells by multiplexed Raman imaging.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Han ZhangDepartment of Biological Engineering, Utah State University, Logan, UT 84322-4105, USA. han.zhang1985@aggiemail.usu.edu.ORCID 0000-0002-9991-9409
Wei ZhangDepartment of Biological Engineering, Utah State University, Logan, UT 84322-4105, USA. wei.zhang@aggiemail.usu.edu.ORCID 0000-0002-1326-6700
Lifu XiaoDepartment of Biological Engineering, Utah State University, Logan, UT 84322-4105, USA. lfxiao0517@gmail.com.ORCID 0000-0002-0320-2076
Yan LiuDepartment of Internal Medicine, University Central Florida, Orlando, FL 32827-7408, USA. Yan.liu@ucf.edu.
Timothy A GilbertsonDepartment of Internal Medicine, University Central Florida, Orlando, FL 32827-7408, USA. Timothy.Gilbertson@ucf.edu.
Anhong ZhouDepartment of Biological Engineering, Utah State University, Logan, UT 84322-4105, USA. Anhong.Zhou@usu.edu.ORCID 0000-0001-6645-6375
Utah State University · USUniversity of Central Florida · US

Funding

FATTY ACID RECEPTORS IN GUSTATIONR01DC013318 · NIDCD · UTAH STATE UNIVERSITY · PI GILBERTSON, TIMOTHY A. · 2014 to 2018
$1.5M
National Science Foundation 1264498NIDCD NIH HHS R01 DC013318NIH HHS R01DC013318
6 · The paper itself

Abstract

In this study, 4-mercaptobenzoic acid (MBA)-Au nanorods conjugated with a GPR120 antibody were developed as a highly sensitive surface-enhanced Raman spectroscopy (SERS) probe, and were applied to detect the interaction of fatty acids (FA) and their cognate receptor, GPR120, on the surface of human embryonic kidney cells (HEK293-GPRR120) cultured in a polydimethylsiloxane (PDMS) microfluidic device. Importantly, the two dominant characteristic SERS peaks of the Raman reporter molecule MBA, 1078 cm

Indexed as

4-mercaptobenzoic acidfatty acidGPR120microfluidicsRamanSERS

Identifiers

PMID30965560
PMCPMC6480160
OpenAlexW2926650535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.