Evidence map›Paper›PMID 30965036›Full record

ArticleDevelopmental cell2019

The Bacterivore's Solution: Fight and Flight to Promote Survival.

Yi-Tang Lee, Meng C Wang

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Yi-Tang LeeIntegrative Program in Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, TX 77030, USA; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.
Meng C WangIntegrative Program in Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, TX 77030, USA; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: wmeng@bcm.edu.

Funding

Decode the chemical language that orchestrates cellular and organismal homeostasisDP1DK113644 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI WANG, MENG CARLA · 2016 to 2020
$5.5M
Targeting a lipid-mediated pro-longevity pathway as Alzheimer's therapyRF1AG062257 · NIA · BAYLOR COLLEGE OF MEDICINE · PI WANG, JIN, WANG, MENG CARLA · 2018 to 2020
$4.0M
LIPID SIGNALING IN REGULATION OF LONGEVITYR01AG045183 · NIA · BAYLOR COLLEGE OF MEDICINE · PI WANG, MENG CARLA · 2013 to 2017
$1.8M
NIA NIH HHS R01 AG045183NIDDK NIH HHS DP1 DK113644
6 · The paper itself

Abstract

Bacterial avoidance and innate immune response are two ways by which C. elegans respond to pathogenic bacteria. In this issue of Developmental Cell, Kumar et al. (2019) and Singh and Aballay (2019) demonstrate that bacterial colonization is essential to induce both responses, which may be associated with somatic and reproductive longevity.

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsImmunity, InnateLongevitySignal TransductionCaenorhabditis elegans Proteins

Identifiers

PMID30965036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.