Evidence map›Paper›PMID 30964962›Full record

ArticleJournal of tissue engineering and regenerative medicine2019

Vitrification and storage of oral mucosa epithelial cell sheets.

Joan Oliva, Arjie Florentino, Fawzia Bardag-Gorce, Yutaka Niihara

Open access · hybridAbstract read
In one paragraph

Article in Journal of tissue engineering and regenerative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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  10. Vitrification and storage of oral mucosa epithelial cell sheets.Journal of tissue engineering and regenerative medicine · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joan OlivaDepartment of Research & Development, Emmaus Medical, Inc., Torrance, CA.ORCID 0000-0001-8900-7126
Arjie FlorentinoDepartment of Medicine, LA BioMed at Harbor UCLA Medical Center, Torrance, CA.
Fawzia Bardag-GorceDepartment of Medicine, LA BioMed at Harbor UCLA Medical Center, Torrance, CA.
Yutaka NiiharaDepartment of Research & Development, Emmaus Medical, Inc., Torrance, CA.
The Lundquist Institute · USTorrance Memorial Medical Center · US

Funding

Emmaus Medical, Inc.
6 · The paper itself

Abstract

Shipping time and shipping delays might affect the quality of the stem cells based engineered "organs." In our laboratory, we have developed a limbal stem cell deficient (LSCD) rabbit model. To reverse the LSCD, we cultured oral mucosal epithelial cells for 2-3 weeks and engineered cultured autologous oral mucosa epithelial cell sheets (CAOMECS), which were grafted on the LSCD cornea. The purpose of this study was to vitrify CAOMECS and to store it until the CAOMECS can be grafted onto patients. CAOMECS were vitrified in LN

Indexed as

Epithelial CellsGene Expression RegulationMouth MucosaPreservation, BiologicalAnimalsAntigens, DifferentiationRabbitsAntigens, Differentiationcell sheetscold storagecryoprotective agentoral mucosa epithelial cellsstem cellsvitrification

Identifiers

PMID30964962
PMCPMC6767061
OpenAlexW2939000673

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.