ArticlePloS one2019
Comparison of wide field optical coherence tomography angiography with extended field imaging and fluorescein angiography in retinal vascular disorders.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 41 citations in OpenAlex.
- Ultra-widefield optical coherence tomography angiography in diabetic retinopathy: from retinal lesions to choroidal metrics.Frontiers in medicine · 2026Review
- Quantitative comparison of a novel wide-field OCT-angiography device with ultrawide-field fluorescein angiography in detecting retinal nonperfusion in vascular retinopathies.BMC ophthalmology · 2025Article
- THE FEASIBILITY OF ULTRA-WIDEFIELD SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY TO GUIDE LASER PHOTOCOAGULATION IN RETINAL VASCULAR DISEASES.Retina (Philadelphia, Pa.) · 2025Article
- The Role of Widefield Optical Coherence Tomography Angiography in Assessing the Severity of Diabetic Retinopathy.Ophthalmology and therapy · 2024Article
- Expanded field: filling the gap between macula and widefield.Eye (London, England) · 2024Article
- Wide - Field optical coherence tomography angiography in florid proliferative diabetic retinopathy.American journal of ophthalmology case reports · 2024Article
- Advantages of the Utilization of Wide-Field OCT and Wide-Field OCT Angiography in Clinical Practice.Diagnostics (Basel, Switzerland) · 2024Review
- Compartmental analysis of retinal vascular parameters and thickness in myopic eyes using SS-OCTA.Frontiers in medicine · 2024Article
- Evaluation of childhood developingWorld journal of clinical cases · 2023Article
- Optical Coherence Tomography Angiography in Retinal Vascular Disorders.Diagnostics (Basel, Switzerland) · 2023Review
- Wide-field swept-source OCTA in the assessment of retinal microvasculature in early-stage diabetic retinopathy.BMC ophthalmology · 2022Observational
- Review
- Clinical Applications of Optical Coherence Tomography Angiography in Ocular Oncology: Pearls and Pitfalls.Ocular oncology and pathology · 2022Review
- Is there a gold standard to assess haemodynamic retina perfusion?Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021Article
- Observation of fundus and optical coherence tomography angiography manifestations in carotid cavernous fistula patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Observation of retinal neovascularization using optical coherence tomography angiography after panretinal photocoagulation for proliferative diabetic retinopathy.BMC ophthalmology · 2021Article
- Multimodal Imaging of Microvascular Abnormalities in Retinal Vein Occlusion.Journal of clinical medicine · 2021Review
- Correlation between the Nonperfusion Area on Ultra-Widefield Fluorescein Angiography and Nonflow Area on Optical Coherence Tomographic Angiography in Retinal Vein Occlusion.Journal of ophthalmology · 2021Article
- Reviewing the Role of Ultra-Widefield Imaging in Inherited Retinal Dystrophies.Ophthalmology and therapy · 2020Review
- Automatic protocol for quantifying the vasoconstriction in blood vessel images.Biomedical optics express · 2020Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare swept source OCTA device, with and without the extended field imaging (EFI) technique, to standard fluorescein angiography (FA) in the clinical practice.
methodsConsecutive patients with vascular disorder patients underwent FA with 55-degree lens (Spectralis Heidelberg Engineering, Heidelberg, Germany) and OCTA with the prototype PlexElite (Carl Zeiss Meditec, Dublin, CA) using a 12 mm x 12 mm volume scan pattern centered on the fovea and a prototype of + 20.00-diopter designed specifically by Zeiss. The imaging methods were compared for visible field of view, extension of non-perfused areas, presence and number of neovessels, vessel density (VD) and fractal dimension (FD).
resultsForty-three eyes of 27 patients were included. The mean extension ratio of EFI SS-OCTA compared to SS-OCTA without EFI and FA were 1.97 ± 0.02 and 0.85 ± 0.01. The mean extension of non-perfused areas with EFI SS-OCTA (34.22 ± 33.4 mm2) was significantly higher than SS-OCTA without EFI (20.46 ± 18.70 mm2), and with FA (27.55 ± 4.4 mm2). The mean VD and FD of EFI SS-OCTA were significantly different compared to SS-OCT without EFI.
conclusionsEFI SS-OCTA captured larger areas than SS-OCTA without EFI and FA. OCTA in a single shot is able to obtain more information of the retina without the use of montage techniques. Despite the determination of retinal ischemia seems to be easier and more accurate using EFI SS-OCTA, FA offers more details of the perfusion status of the retina.
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