ArticlePloS one2019
Associations of medical conditions, lifestyle and unintentional weight loss in early old age: The 1946 British Birth Cohort.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- Circulating metabolomic biomarkers of 5-year body weight and composition change in a biracial cohort of community-dwelling older adults.GeroScience · 2025Article
- Metabolomic characterization of unintentional weight loss among community-dwelling older Black and White men and women.Aging cell · 2025Article
- Construction of a comprehensive nutritional index and comparison of its prognostic performance with the PNI and NRI for survival in older patients with nasopharyngeal carcinoma: a retrospective study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Factors associated with unintentional weight loss among older adults in a geriatric outpatient clinic of university hospital.PloS one · 2021Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundUnintentional weight loss in older people has been linked to increased risk of mortality. We aimed to investigate common medical conditions and lifestyle factors, including body fat distribution, as potential determinants of recent and prospective unintentional weight loss in early old age.
methodsFrom the Medical Research Council (MRC) National Survey of Health and Development (NSHD), we included a total of 2234 study members aged 60-64 with information on unintentional weight loss in 2006-2010. Of these, 2136 also had information on unintentional weight loss recorded in 2015. Logistic regression was conducted to examine the associations between medical conditions, lifestyle, and body fat distribution at age 60-64 and unintentional weight loss at age 60-64 and 69.
resultsA total of 109 of 2234 study members had unintentional weight loss at ages 60-64, and 166 of 2136 at age 69. Never smoking was associated with lower risk of unintentional weight loss at age 60-64 (OR = 0.29, 95%CI = 0.12-0.68 compared to current smokers), and this association remained when adjusted for other determinants. Greater waist-hip ratio (OR = 0.95, 95%CI = 0.91-0.99) and body fat-lean mass ratio (OR = 0.96, 95%CI = 0.94-0.99) were associated with less likelihood of unintentional weight loss at age 60-64. Never smoking and greater hip circumference at age 60-64 were associated with lower odds of unintentional weight loss at age 69.
conclusionsSmoking status and body fat distribution may help identify those at risk of unintentional weight loss in early old age. Their benefit in interventions to prevent age-associated weight loss needs to be further investigated.
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