Evidence map›Paper›PMID 30964816›Full record

ArticleEpidemiology (Cambridge, Mass.)2019

A Pooled Analysis of Breastfeeding and Breast Cancer Risk by Hormone Receptor Status in Parous Hispanic Women.

Meera Sangaramoorthy, Lisa M Hines, Gabriela Torres-Mejía, Amanda I Phipps, Kathy B Baumgartner, Anna H Wu, Jocelyn Koo, Sue A Ingles, Martha L Slattery, Esther M John

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology (Cambridge, Mass.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

Meera SangaramoorthyFrom the Cancer Prevention Institute of California, Fremont, CA.
Lisa M HinesDepartment of Biology, University of Colorado at Colorado Springs, Colorado Springs, CO.
Gabriela Torres-MejíaInstituto Nacional de Salud Pública, Population Health Research Center, Cuernavaca Morelos, Mexico.
Amanda I PhippsDepartment of Epidemiology, University of Washington, Seattle, WA.
Kathy B BaumgartnerDepartment of Epidemiology and Population Health, School of Public Health & Information Sciences, James Graham Brown Cancer Center, University of Louisville, Louisville, KY.
Anna H WuDepartment of Preventive Medicine, Keck School of Medicine of USC, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA.
Jocelyn KooFrom the Cancer Prevention Institute of California, Fremont, CA.
Sue A InglesDepartment of Preventive Medicine, Keck School of Medicine of USC, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA.
Martha L SlatteryDepartment of Medicine, University of Utah, Salt Lake City, UT.
Esther M JohnFrom the Cancer Prevention Institute of California, Fremont, CA.
Stanford University · USUniversity of Southern California · USCancer Prevention Institute of California · USFred Hutch Cancer Center · USInstituto Nacional de Salud Pública · MXUniversity of Colorado Colorado Springs · USUniversity of Louisville · USUniversity of Utah · US

Funding

CALIFORNIA'S PARTICIPATION IN THE NATIONAL CANCER PREVENTION AND CONTRO PROGRAMU58DP000807 · DP · PUBLIC HEALTH INSTITUTE · PI SNIPES, KURT P · 2007 to 2011
$22.5M
Core-001U01CA164920 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Irene Andrulis, Sarah Violet Colonna · 2018 to 2026
$17.0M
Breast Cancer Family Registry CohortUM1CA164920 · NCI · CANCER PREVENTION INSTIT OF CALIFORNIA · PI ANDRULIS, IRENE, BUYS, SAUNDRA S · 2012 to 2017
$12.7M
FOUR-CORNERS BREAST AND ENDOMETRIAL CANCER STUDYR01CA078682 · NCI · UNIVERSITY OF UTAH · PI SLATTERY, MARTHA OR MARTY L · 1999 to 2003
$4.0M
Disparities in Breast Cancer: Development and Survival in Hispanic and NHW WomenR01CA140002 · NCI · UNIVERSITY OF UTAH · PI SLATTERY, MARTHA L · 2009 to 2013
$3.1M
THE 4 CORNERS BREAST AND ENDOMETRIAL CANCER STUDYR01CA078762 · NCI · UNIVERSITY OF NEW MEXICO · PI BAUMGARTNER, KATHY B · 1999 to 2003
$3.0M
FOUR-CORNERS BREAST AND ENDOMETRIAL CANCER STUDYR01CA078802 · NCI · UNIVERSITY OF ARIZONA · PI MARTINEZ, MARIA ELENA · 1999 to 2003
$2.2M
FOUR-CORNERS BREAST CANCER STUDYR01CA078552 · NCI · UNIVERSITY OF COLORADO DENVER · PI BYERS, TIM E · 1999 to 2003
$1.5M
Risk factors for breast cancer subtypes in racial/ethnic minoritiesR03CA199343 · NCI · CANCER PREVENTION INSTIT OF CALIFORNIA · PI JOHN, ESTHER M. · 2015 to 2016
$149k
BREAST CANCER RISK FACTORS IN HISPANIC WOMENR01CA063446 · NCI · NORTHERN CALIFORNIA CANCER CENTER · PI JOHN, ESTHER M · 1995 to 1998
–
NCCDPHP CDC HHS U58 DP000807NCI NIH HHS HHSN261201000036CNCI NIH HHS R01 CA063446NCI NIH HHS R01 CA078552NCI NIH HHS R01 CA078682NCI NIH HHS R01 CA078762NCI NIH HHS R01 CA078802NCI NIH HHS R01 CA140002NCI NIH HHS R03 CA199343NCI NIH HHS U01 CA164920NCI NIH HHS UM1 CA164920
6 · The paper itself

Abstract

backgroundData on breastfeeding and breast cancer risk are sparse and inconsistent for Hispanic women.

methodsPooling data for nearly 6,000 parous Hispanic women from four population-based studies conducted between 1995 and 2007 in the United States and Mexico, we examined the association of breastfeeding with risk of breast cancer overall and subtypes defined by estrogen receptor (ER) and progesterone receptor (PR) status, and the joint effects of breastfeeding, parity, and age at first birth. We calculated odds ratios (ORs) and 95% confidence intervals (CIs) using logistic regression.

resultsAmong parous Hispanic women, older age at first birth was associated with increased breast cancer risk, whereas parity was associated with reduced risk. These associations were found for hormone receptor positive (HR+) breast cancer only and limited to premenopausal women. Age at first birth and parity were not associated with risk of ER- and PR- breast cancer. Increasing duration of breastfeeding was associated with decreasing breast cancer risk (≥25 vs. 0 months: OR = 0.73; 95% CI = 0.60, 0.89; Ptrend = 0.03), with no heterogeneity by menopausal status or subtype. At each parity level, breastfeeding further reduced HR+ breast cancer risk. Additionally, breastfeeding attenuated the increase in risk of HR+ breast cancer associated with older age at first birth.

conclusionsOur findings suggest that breastfeeding is associated with reduced risk of both HR+ and ER- and PR- breast cancer among Hispanic women, as reported for other populations, and may attenuate the increased risk in women with a first pregnancy at older ages.

Indexed as

ParityAdultAgedBreast FeedingBreast NeoplasmsFemaleHispanic or LatinoHumansMexicoMiddle AgedPregnancyReceptors, EstrogenReceptors, ProgesteroneRisk FactorsUnited StatesReceptors, EstrogenReceptors, Progesterone

Identifiers

PMID30964816
PMCPMC6472273
OpenAlexW2917395367

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.