Evidence map›Paper›PMID 30964804›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2019

How Can Programs Better Support Female Sex Workers to Avoid HIV Infection in Zimbabwe? A Prevention Cascade Analysis.

Elizabeth Fearon, Andrew Phillips, Sibongile Mtetwa, Sungai T Chabata, Phillis Mushati, Valentina Cambiano, Joanna Busza, Sue Napierala, Bernadette Hensen, Stefan Baral and 4 more

Abstract readPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  16. Stigma, Social Support, and Sexual Behavior Among Female Sex Workers at Risk for HIV in Malawi.AIDS education and prevention : official publication of the International Society for AIDS Education · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elizabeth FearonDepartment of Social and Environmental Health Research, Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Andrew PhillipsInstitute for Global Health, Faculty of Population Health Sciences, University College London, London, United Kingdom.
Sibongile MtetwaCentre for Sexual Health and HIV AIDS Research (CeSHHAR) Zimbabwe, Harare, Zimbabwe.
Sungai T ChabataCentre for Sexual Health and HIV AIDS Research (CeSHHAR) Zimbabwe, Harare, Zimbabwe.
Phillis MushatiCentre for Sexual Health and HIV AIDS Research (CeSHHAR) Zimbabwe, Harare, Zimbabwe.
Valentina CambianoInstitute for Global Health, Faculty of Population Health Sciences, University College London, London, United Kingdom.
Joanna BuszaDepartment of Social and Environmental Health Research, Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Sue NapieralaWomen's Global Health Imperative, RTI International, San Francisco, CA.
Bernadette HensenDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Stefan BaralBloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.
Sharon S WeirDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Brian RiceDepartment of Social and Environmental Health Research, Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Frances M CowanCentre for Sexual Health and HIV AIDS Research (CeSHHAR) Zimbabwe, Harare, Zimbabwe.
James R HargreavesDepartment of Social and Environmental Health Research, Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.

Funding

Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
HIV Prevention among Young Female Sex Workers: an Implementation Research ApproachK01MH110316 · NIMH · RESEARCH TRIANGLE INSTITUTE · PI NAPIERALA, SUE · 2016 to 2019
$753k
NICHD NIH HHS P2C HD050924NIMH NIH HHS K01 MH110316
6 · The paper itself

Abstract

background"HIV prevention cascades" have been proposed to support programs by identifying gaps in demand for, access to, and capability to adhere to HIV prevention tools, but there are few empirical examples to guide development. We apply a prevention cascade framework to examine prevention coverage and factors associated with condoms and/or PrEP adherence among female sex workers.

settingSeven sites across Zimbabwe.

methodsSeven respondent-driven sampling surveys from the intervention sites of a pragmatic cluster-randomized trial in Zimbabwe in 2016 were analyzed, and 611/1439 women testing HIV-negative included. We operationalized key components of an HIV prevention cascade including demand, supply, and capability to adhere to 2 tools for HIV prevention: condoms and pre-exposure prophylaxis (PrEP). We used adjusted logistic regression to identify determinants of adherence to condoms and PrEP in turn, examining the effect of adherence to one tool on adherence to the other.

resultsThere were 343/611, 54.7%, women reporting adherence to condoms and/or PrEP, leaving almost half uncovered. Although women were aware that condoms prevented HIV and reported good access to them, only 45·5% reported full adherence to condom use. For PrEP, a new technology, there were gaps along all 3 domains of demand, supply, and adherence. Alcohol use decreased adherence to PrEP and condoms. Younger and newer entrants to sex work were less likely to take PrEP every day.

conclusionsHIV prevention programming among female sex workers in Zimbabwe could consider increasing awareness of PrEP alongside supply, alcohol use interventions, and approaches to engaging younger women.

Indexed as

Sex WorkersAdultAnti-HIV AgentsCondomsDrug MonitoringFemaleHIV InfectionsHumansPre-Exposure ProphylaxisUnsafe SexZimbabweAnti-HIV Agents

Identifiers

PMID30964804
PMCPMC6467580

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.