Evidence map›Paper›PMID 30964568›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2019

Hyperpolarizing Concentrated Metronidazole

Roman V Shchepin, Jonathan R Birchall, Nikita V Chukanov, Kirill V Kovtunov, Igor V Koptyug, Thomas Theis, Warren S Warren, Juri G Gelovani, Boyd M Goodson, Sepideh Shokouhi and 4 more

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. High-resolution microtesla in-situJournal of magnetic resonance (San Diego, Calif. : 1997) · 2026
    Article
  2. Article
  3. Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  4. The journal of physical chemistry. B · 2025
    Article
  5. The journal of physical chemistry. B · 2025
    Article
  6. EfficientJournal of magnetic resonance open · 2025
    Article
  7. Article
  8. The journal of physical chemistry. B · 2025
    Article
  9. Article
  10. The journal of physical chemistry letters · 2024
    Article
  11. Molecules, Up Your Spins!Molecules (Basel, Switzerland) · 2024
    Article
  12. Article
  13. Article
  14. Development of Dissolution Dynamic Nuclear Polarization of [Angewandte Chemie (International ed. in English) · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. RapidAnalytical chemistry · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Roman V ShchepinDepartment of Radiology, Vanderbilt University Institute of Imaging Science (VUIIS), Vanderbilt University Medical Center (VUMC), Nashville, Tennessee, 37232-2310, USA.ORCID http://orcid.org/0000-0001-9135-3036
Jonathan R BirchallDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan, 48202, USA.
Nikita V ChukanovInternational Tomography Center, SB RAS, 3A Institutskaya St., Novosibirsk, 630090, Russia.ORCID http://orcid.org/0000-0003-1246-8869
Kirill V KovtunovInternational Tomography Center, SB RAS, 3A Institutskaya St., Novosibirsk, 630090, Russia.ORCID http://orcid.org/0000-0001-7577-9619
Igor V KoptyugInternational Tomography Center, SB RAS, 3A Institutskaya St., Novosibirsk, 630090, Russia.ORCID http://orcid.org/0000-0003-3480-7649
Thomas TheisDepartment of Chemistry, North Carolina State University, Raleigh, North Carolina, 27695-8204, USA.ORCID http://orcid.org/0000-0001-6779-9978
Warren S WarrenDepartment of Chemistry, Duke University, Durham, North Carolina, 27708, USA.ORCID http://orcid.org/0000-0001-8458-2076
Juri G GelovaniDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan, 48202, USA.ORCID http://orcid.org/0000-0002-8413-6161
Boyd M GoodsonDepartment of Chemistry and Biochemistry and Materials Technology Center, Southern Illinois University, Carbondale, Illinois, 62901, USA.ORCID http://orcid.org/0000-0001-6079-5077
Sepideh ShokouhiDepartment of Radiology, Vanderbilt University Institute of Imaging Science (VUIIS), Vanderbilt University Medical Center (VUMC), Nashville, Tennessee, 37232-2310, USA.ORCID http://orcid.org/0000-0001-6904-1861
Matthew S RosenMassachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts, 02129, USA.ORCID http://orcid.org/0000-0002-7194-002X
Yi-Fen YenMassachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts, 02129, USA.ORCID http://orcid.org/0000-0001-9986-5327
Wellington PhamDepartment of Radiology, Vanderbilt University Institute of Imaging Science (VUIIS), Vanderbilt University Medical Center (VUMC), Nashville, Tennessee, 37232-2310, USA.
Eduard Y ChekmenevDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan, 48202, USA.ORCID http://orcid.org/0000-0002-8745-8801

Funding

Multifunctional Nanoparticles for Image-Guided Vaccine Delivery in CancerR01CA160700 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PHAM, WELLINGTON · 2012 to 2015
$1.3M
Magnetic Resonance Spectroscopy and Molecular Imaging of Metabolic Pathways in CancerR21CA220137 · NCI · WAYNE STATE UNIVERSITY · PI CHEKMENEV, EDUARD · 2017 to 2019
$390k
Congressionally Directed Medical Research Programs W81XWH-12-1-0159/BC112431Directorate for Mathematical and Physical Sciences CHE-1416432Directorate for Mathematical and Physical Sciences CHE-1836308DOD Peer Reviewed Cancer Research Program W81XWH-15-1-0271DOD Peer Reviewed Cancer Research Program W81XWH-15-1-0272National Cancer Institute R01CA16700National Cancer Institute R21CA220137NCI NIH HHS R01 CA160700NCI NIH HHS R21 CA220137Russian Ministry of Science and Higher Education 0267-2019-0004Russian Ministry of Science and Higher Education AAAA-A16-116121510087-5Russian Science Foundation 17-73-20030
6 · The paper itself

Abstract

The NMR hyperpolarization of uniformly

Indexed as

hyperpolarizationisotopic labelingnitrogen heterocyclesNMR spectroscopySABREspin relays

Identifiers

PMID30964568
PMCPMC6658333

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.