Evidence map›Paper›PMID 30964225›Full record

SynthesisThe International journal of pharmacy practice2019

Factors associated with potentially inappropriate medication use in community-dwelling older adults in the United States: a systematic review.

Stephanie K Nothelle, Ritu Sharma, Allison Oakes, Madeline Jackson, Jodi B Segal

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The International journal of pharmacy practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Use of potentially inappropriate medication for elderly patients in tertiary care hospital of Riyadh, Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephanie K NothelleDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0003-3908-286X
Ritu SharmaJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Allison OakesJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Madeline JacksonJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Jodi B SegalDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Funding

Towards Understanding the Patient Experience of Overuse of Medical ResourcesK24AG049036 · NIA · JOHNS HOPKINS UNIVERSITY · PI SEGAL, JODI B. · 2015 to 2024
$1.6M
AHRQ HHS T32 HS000029NIA NIH HHS K24 AG049036NIA NIH HHS K24 AG049036-01A1
6 · The paper itself

Abstract

objectivesPotentially inappropriate medication (PIM) use in older adults is a prevalent problem associated with poor health outcomes. Understanding drivers of PIM use is essential for targeting interventions. This study systematically reviews the literature about the patient, clinician and environmental/system factors associated with PIM use in community-dwelling older adults in the United States.

methodsPRISMA guidelines were followed when completing this review. PubMed and EMBASE were queried from January 2006 to September 2017. Our search was limited to English-language studies conducted in the United States that assessed factors associated with PIM use in adults ≥65 years who were community-dwelling. Two independent reviewers screened titles and abstracts. Reviewers abstracted data sequentially and assessed risk of bias independently. KEY

findingsTwenty-two studies were included. Nineteen examined patient factors associated with PIM use. The most common statistically significant factors associated with PIM use were taking more medications, female sex, and higher outpatient and emergency department utilization. Only three studies examined clinician factors, and few were statistically significant. Fifteen studies examined system-level factors such as geographic region and health insurance. The most common statistically significant association was the south and west geographic region relative to the northeast United States.

conclusionsAmongst older adults, women and persons on more medications are at higher risk of PIM use. There is evidence that increased healthcare use is also associated with PIM use. Future studies are needed exploring clinician factors, such as specialty, and their association with PIM prescribing.

Indexed as

Independent LivingAgedAged, 80 and overFemaleHumansInappropriate PrescribingMalePolypharmacyPotentially Inappropriate Medication ListSex FactorsUnited Statesgeriatric ambulatory carepotentially inappropriate medications

Identifiers

PMID30964225
PMCPMC7938818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.