Evidence map›Paper›PMID 30964090›Full record

ArticleThe Indian journal of medical research2018

Role of environmental factors & oxidative stress with respect to

Sunil Kumar, Vineet Mishra, Riddhi Thaker, Mansi Gor, Siva Perumal, Pratiksha Joshi, Hardik Sheth, Idrish Shaikh, Anil K Gautam, Yogendra Verma

Open access · diamondAbstract read
In one paragraph

Article in The Indian journal of medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Influence of Seminal Metals on Assisted Reproduction Outcome.Biological trace element research · 2023
    Article
  10. Review
  11. An Overview of Essential Microelements and Common Metallic Nanoparticles and Their Effects on Male Fertility.International journal of environmental research and public health · 2022
    Review
  12. Heavy metals and metalloids exposure andFrontiers in reproductive health · 2022
    Review
  13. Article
  14. Impact of Heavy Metals on Human Male Fertility-An Overview.Antioxidants (Basel, Switzerland) · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Zygotic genome activation in the chicken: a comparative review.Cellular and molecular life sciences : CMLS · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sunil KumarDivision of Reproductive and Cytotoxicology, ICMR-National Institute of Occupational Health, Ahmedabad, India.
Vineet MishraDepartment of Gynaecology & Obstetrics, IVF Centre, Institute of Kidney Diseases and Research Centre, Ahmedabad, India.
Riddhi ThakerDivision of Reproductive and Cytotoxicology, ICMR-National Institute of Occupational Health, Ahmedabad, India.
Mansi GorDivision of Reproductive and Cytotoxicology, ICMR-National Institute of Occupational Health, Ahmedabad, India.
Siva PerumalDivision of Pesticide, ICMR-National Institute of Occupational Health, Ahmedabad, India.
Pratiksha JoshiDepartment of Gynaecology & Obstetrics, IVF Centre, Institute of Kidney Diseases and Research Centre, Ahmedabad, India.
Hardik ShethDepartment of Gynaecology & Obstetrics, IVF Centre, Institute of Kidney Diseases and Research Centre, Ahmedabad, India.
Idrish ShaikhDivision of Occupational Hygiene, ICMR-National Institute of Occupational Health, Ahmedabad, India.
Anil K GautamDivision of Reproductive and Cytotoxicology, ICMR-National Institute of Occupational Health, Ahmedabad, India.
Yogendra VermaDivision of Reproductive and Cytotoxicology, ICMR-National Institute of Occupational Health, Ahmedabad, India.
National Institute of Occupational Health · INInstitute of Transplantation Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & objectives: Oxidative stress, lifestyle factors as also exposure to certain environmental factors are known to affect the fertility status in human beings. The aim of this study was to evaluate the role of OS and lifestyle and environmental factors affecting IVF outcome. Methods: A total of 253 couples were included, and biological samples such as blood, follicular fluid (FF), cumulus cells and semen were collected. Relevant biochemical parameters and metals namely lead (Pb), cadmium (Cd), copper (Cu) and zinc (Zn) were determined in the biological samples. β-human chorionic gonadotropin levels ≥100 IU/l were considered to predict viable pregnancy on the 15 Results: The mean body mass index (BMI) was significantly lower in females with positive IVF outcome compared to those with negative outcome. Couples residing in the residential area showed more percentage of positive IVF outcomes as compared to couples residing in industrial/agricultural area. FF Zn level was significantly higher (P<0.001) among the females' participants who have undergone ET as compared to those who have not undergone ET. FF MDA and serum Cu levels were significantly higher (P<0.05) in the female participants with negative IVF outcome as compared to positive IVF outcome. Logistic regression revealed that maternal BMI (P=0.034) and FF MDA level (P=0.047) were significantly associated with the IVF outcome. Interpretation & conclusions: The success rate of IVF was about 31.8 per cent, and BMI was significantly lower in females with positive outcome. The higher levels of MDA in FF and SP might have a negative impact on IVF outcome, higher Zn level in SP, FF and serum might have a positive role in embryo transfer as well as IVF outcome. The role of stress management and nutrition supplementation during the IVF treatment may be explored.

Indexed as

AdultBody Mass IndexChorionic GonadotropinDNA DamageEmbryo TransferEndometriosisFemaleFertilization in VitroFollicular FluidHumansMaleMetals, HeavyOocyte RetrievalOocytesOxidative StressPregnancyChorionic GonadotropinMetals, HeavyZincDNA damageembryo transferheavy metals and trace metalsin vitro fertilization outcomeoocyte retrievaloxidative stressβ-human chorionic gonadotropin

Identifiers

PMID30964090
PMCPMC6469366
OpenAlexW2953181308

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.