Evidence map›Paper›PMID 30964082›Full record

ReviewThe Indian journal of medical research2018

Postpartum uterine infection & ovarian dysfunction.

Sunita Dahiya, Suman Kumari, Payal Rani, Suneel Kumar Onteru, Dheer Singh

Open access · diamondAbstract readReview
In one paragraph

Review in The Indian journal of medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sunita DahiyaMolecular Endocrinology, Functional Genomics & System Biology Laboratory, Animal Biochemistry Division, ICAR-National Dairy Research Institute, Karnal, India.
Suman KumariMolecular Endocrinology, Functional Genomics & System Biology Laboratory, Animal Biochemistry Division, ICAR-National Dairy Research Institute, Karnal, India.
Payal RaniMolecular Endocrinology, Functional Genomics & System Biology Laboratory, Animal Biochemistry Division, ICAR-National Dairy Research Institute, Karnal, India.
Suneel Kumar OnteruMolecular Endocrinology, Functional Genomics & System Biology Laboratory, Animal Biochemistry Division, ICAR-National Dairy Research Institute, Karnal, India.
Dheer SinghMolecular Endocrinology, Functional Genomics & System Biology Laboratory, Animal Biochemistry Division, ICAR-National Dairy Research Institute, Karnal, India.
National Dairy Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postpartum uterine infections such as metritis, endometritis and mastitis have been considered as underlying causes for ovarian dysfunction in mammals. Almost all mammals, particularly dairy animals are susceptible to postpartum uterine infections, resulting in impaired fertility and economic loss. One of the factors for low fertility in females is ovarian dysfunction, which is exhibited as impaired growth and function of ovarian follicles by the postpartum infection. Immune system of mammals provides a host defence mechanism against pathogenic microbes through the recognition of pathogen-associated molecular patterns (PAMPs) and forming inflammasomes. Like immune cells, ovarian granulosa cells also exhibit a similar pattern of cytokine gene expressions on exposure to PAMPs. Genome-wide transcriptomic approaches explored the molecular mechanisms underlying the immune function of buffalo granulosa cells during endotoxin exposure. Understanding the molecular mechanism of ovarian dysfunction due to uterine infection would be helpful to implement various strategies to handle the adverse effects of postpartum uterine disease on fertility by developing potential therapeutics. Therefore, this article focuses on key factors that are responsible for postpartum infection and particularly summarizes the molecular mechanism of infection underlying the ovarian dysfunction in dairy animals.

Indexed as

AnimalsCattleEndometritisFemaleFertilityInfectionsMastitisPostpartum PeriodUterine DiseasesUterusEndotoxingranulosa cellsovarian dysfunctionpostpartum periodtoll-like receptorsuterine infection

Identifiers

PMID30964082
PMCPMC6469370
OpenAlexW2981316996

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.