ArticleProceedings. Biological sciences2019
Experimental evolution of parasitic host manipulation.
Article in Proceedings. Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- The Evolution and Ecology of Host Manipulation in Helminth Parasites: A Phylogenetic Meta-Analysis.Ecology letters · 2026Pooled it
- Scientists' Warning on the Rapid Evolution of Parasites in the Anthropocene.Evolutionary applications · 2026Article
- Parasite-mediated predation determines infection in a complex predator-prey-parasite system.Proceedings. Biological sciences · 2024Article
- Laser-based selective killing of a manipulative parasite reveals partial reversibility of phenotypic alterations in its intermediate host.Current research in parasitology & vector-borne diseases · 2024Article
- Model worms: knowledge gains and risks associated with the use of model species in parasitological research.Parasitology · 2023Review
- Six new species of zombie-ant fungi from Yunnan in China.IMA fungus · 2023Article
- Allee effect in a manipulative parasite within poikilothermic host under temperature change.Parasitology · 2022Article
- Genetic Underpinnings of Host Manipulation byG3 (Bethesda, Md.) · 2020Article
- Tapeworm manipulation of copepod behaviour: parasite genotype has a larger effect than host genotype.Biology letters · 2019Article
- Behavior out of control: Experimental evolution of resistance to host manipulation.Ecology and evolution · 2019Article
- Experimental evolution of parasitic host manipulation.Proceedings. Biological sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Host manipulation is a parasite-induced alteration of a host's phenotype that increases parasite fitness. However, if genetically encoded in the parasite, it should be under selection in the parasite. Such host manipulation has often been assumed to be energetically costly, which should restrict its evolution. Evidence of such costs, however, remains elusive. The trophically transmitted cestode Schistocephalus solidus manipulates the activity of its first intermediate copepod host to reduce its predation susceptibility before the parasite is ready for transmission. Thereafter, S. solidus increases host activity to facilitate transmission to its subsequent fish host. I selected S. solidus for or against host manipulation over three generations to investigate the evolvability of manipulation and identify potential trade-offs. Host manipulation responded to selection, confirming that this trait is heritable in the parasite and hence can present an extended phenotype. Changes in host manipulation were not restrained by any obvious costs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.