ArticleProceedings. Biological sciences2019
Direct transmission by injection affects competition among RNA viruses in honeybees.
Article in Proceedings. Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 56 citations in OpenAlex.
- Patterns of viral prevalence and load show independent circulation of some honey bee viruses in wild bees.Scientific reports · 2026Article
- Co-inoculation with deformed wing virus and sacbrood virus affects viral and immune dynamics and synergistically increases honey bee mortality.PLoS pathogens · 2026Article
- Injection but not ingestion of a mixed virus suspension in Queensland fruit fly (Bactrocera tryoni) shifts persistent covert infection to acute pathology.Pest management science · 2026Article
- Bumble Bees and Honey Bees on Islands Harbour Reduced Viral Species Richness, Yet Honey Bee Populations Are Dominated by a Deformed Wing Virus Recombinant.Molecular ecology · 2025Article
- The intensity of the transcriptional response varies across infection with distinct viral strains in an insect host.BMC genomics · 2025Article
- Genotype B of deformed wing virus and related recombinant viruses become dominant in European honey bee colonies.Scientific reports · 2025Article
- Israeli Acute Paralysis Virus Is an Emerging Pathogen Contributing to Brood Disease ofViruses · 2024Article
- Prevalence and molecular analysis of some important viruses in honey bee colonies in Türkiye: the status of multiple infections.Archives of virology · 2024Article
- Caught in the act: the invasion of a viral vector changes viral prevalence and titre in native honeybees and bumblebees.Biology letters · 2024Article
- Eggs sampling as an effective tool for identifying the incidence of viruses in honey bees involved in artificial queen rearing.Scientific reports · 2024Article
- Shift in virus composition in honeybees (Royal Society open science · 2024Article
- Virus replication in the honey bee parasite,Journal of virology · 2023Article
- Signatures of adaptive decreased virulence of deformed wing virus in an isolated population of wild honeybees (Proceedings. Biological sciences · 2023Article
- Emerging threats and opportunities to managed bee species in European agricultural systems: a horizon scan.Scientific reports · 2023Article
- Article
- Review
- The final frontier: ecological and evolutionary dynamics of a global parasite invasion.Biology letters · 2023Review
- Honey Bee Pathogen Prevalence and Interactions within the Marmara Region of Turkey.Veterinary sciences · 2022Article
- Viral species differentially influence macronutrient preferences based on honey bee genotype.Biology open · 2022Article
- Viral communities in the parasite Varroa destructor and in colonies of their honey bee host (Apis mellifera) in New Zealand.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The arrival of the ectoparasitic mite Varroa destructor on the western honeybee Apis mellifera saw a change in the diversity and prevalence of honeybee RNA viruses. One virus in particular, deformed wing virus (DWV) has become closely associated with V. destructor, leading many to conclude that V. destructor has affected viral virulence by changing the mode of transmission. While DWV is normally transmitted via feeding and faeces, V. destructor transmits viruses by direct injection. This change could have resulted in higher viral prevalence causing increased damage to the bees. Here we test the effect of a change in the mode of transmission on the composition and levels of honeybee RNA viruses in the absence of V. destructor. We find a rapid increase in levels of two viruses, sacbrood virus (SBV) and black queen cell virus (BQCV) after direct injection of viral extracts into honeybee pupae. In pupae injected with high levels of DWV extracted from symptomatic adult bees, DWV levels rapidly decline in the presence of SBV and BQCV. Further, we observe high mortality in honeybee pupae when injected with SBV and BQCV, whereas injecting pupae with high levels of DWV results in near 100% survival. Our results suggest a different explanation for the observed association between V. destructor and DWV. Instead of V. destructor causing an increase in DWV virulence, we hypothesize that direct virus inoculation, such as that mediated by a vector, quickly eliminates the most virulent honeybee viruses resulting in an association with less virulent viruses such as DWV.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.